Doctoral student in Affinity-based plasma proteomics

School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH 

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

Science for Life Laboratory (SciLifeLab, https://www.scilifelab.se/) is a national center for large-scale life science research with an advanced technological infrastructure. At SciLifeLab, multidisciplinary research is carried out based on DNA sequencing, gene expression analysis, proteomics, bioinformatics, biostatistics and system biology. The goal is to enable Swedish researchers to analyze genes, transcripts and proteins in different organisms in order to map molecular mechanisms related to health and the environment. Examples of thematic research areas that are currently being processed within SciLifeLab are clinical genomics/proteomics, cancer genome and the genomics of complex diseases as well as ecological and environmental genomics.

Project description

The project will focus on profiling the human proteome in body fluids by utilzing advanced affinity proteomics methods, and on the investigation of emerging biomarkers in relation to states of different diseseas. The doctoral student will work with human blood samples, develop analytical methods and highly multiplexed antibody-based assays, implement bioinformatics methods and perform data analysis. The positions will be focused on aspects of the protein biomarker analysis pipeline, including the experimental study design, assay development, planning and executing the precison measurements for disovery and validation, and analyzing the data within the disease context.

Third-cycle subject: Biotechnology

Supervision: The doctoral student will be supervised by Prof. Jochen Schwenk and co-supervision of Dr. Claudia Fredolini, in close collaboration with the Human Protein Atlas project (www.proteinatlas.org) and the Affinity Proteomics unit consisting of research engineers, postdocs and researchers.

What we offer

• The possibility to study in a dynamic and international research environment in collaboration with industries and prominent universities from all over the world.Read more
• A workplace with many employee benefits and monthly salary according to KTH’s Doctoral student salary agreement.
• A postgraduate education at an institution that is active and supportive in matters pertaining to working conditions, gender equality and diversity as well as study environment.
• Work and study in Stockholm, close to nature and the water.
• Help to relocate and be settled in Sweden and at KTH.
• Work in international research consortia, such as an EU project for precision medicine.

Eligibility

To be admitted to postgraduate education (Chapter 7, 39 § Swedish Higher Education Ordinance), the applicant must have basic eligibility in accordance with either of the following:

• passed a degree at advanced level,
• completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits at advanced level, or
• acquired, in some other way within or outside the country, substantially equivalent knowledge
• Requirements for English equivalent to English B/6, read more here.
• Experience within affinity proteomics and data analysis using R are meriting.

Selection

In order to succeed as a doctoral student at KTH you need to be goal oriented and persevering in your work. During the selection process, candidates will be assessed upon their ability to:

• independently pursue his or her work
• collaborate with others,
• have a professional approach and
• analyse and work with complex issues.

After the qualification requirements, great emphasis will be placed on personal competency. 

Target degree: Doctoral degree

Information regarding admission and employment

Only those admitted to postgraduate education may be employed as a doctoral student. The total length of employment may not be longer than what corresponds to full-time doctoral education in four years ‘ time. An employed doctoral student can, to a limited extent (maximum 20%), perform certain tasks within their role, e.g. training and administration. A new position as a doctoral student is for a maximum of one year, and then the employment may be renewed for a maximum of two years at a time.

Union representatives

You will find contact information for union representatives on KTH’s website.

Doctoral section (Students’ union on KTH Royal Institute of Technology)

You will find contact information for doctoral section on the section’s website.

Application

Apply for the position and admission through KTH’s recruitment system. It is the applicant’s responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Other information

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

For information about processing of personal data in the recruitment process please read here.

We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.

Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.