Doctoral student in Molecular Genomics

KTH

Application deadline

April 30, 2021



Doctoral student in Molecular Genomics

School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH 

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH) is one of the five schools of KTH and a strong constellation for research and education in the broader areas of health, environment, energy and materials. See our homepage: https://www.kth.se/en/cbh

This position is located at Science for Life Laboratory. For more information please se our homepage: https://www.scilifelab.se

Project description 

Third-cycle subject: Gene Technology

The Molecular Genomics lab investigates genome regulation, chromatin architecture and transcriptional mechanisms. We use and develop techniques that track nascent transcription at a nucleotide-resolution, measuring rate-limiting steps of transcription at genes and enhancers. The broad scope of Your project is to gain mechanistic understanding on how chromatin architecture and transcription are coordinated at genes and enhancers, and how cells orchestrate transcriptional program in physiologically relevant settings, such as acute stress responses, differentiation and disease progression.

The Molekylar Genomics laboratory is part of Science for Life Laboratory (http://www.scilifelab.se/), a national center for Natural Sciences in Sweden.

Job assignments 

As a PhD student in Molecular Genomics, you will investigate genome organisation, mechanisms of transcription and cellular responses. You will use and develop advanced biochemical methods and data analytical tools, including run-on, ChIP-seq and ATAC-seq based genome-wide assays. The successful candidate will take a strong lead on planning and performing original research in the fields of cell and molecular biology, genomics and gene technology. You are driven and motivated to understand how transcription is orchestrated at genes and enhancers, and how developmental processes, rapid cellular responses and transcriptional memory are mechanistically regulated in cells and organisms. 

Supervision: Assistant Professor, Anniina Vihervaara.

What we offer

Eligibility

To be admitted to postgraduate education (Chapter 7, 39 § Swedish Higher Education Ordinance), the applicant must have basic eligibility in accordance with either of the following:

  • passed a degree at advanced level,
  • completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits at advanced level, or
  • in any other way acquired within or outside the country acquired essentially equivalent knowledge.
  • Requirements for English equivalent to English B/6, read more here

Requirements

  • Master of Sciences degree in cell biology, molecular biology, biotechnology, bioinformatics or a related topic.
  • Laboratory experience in cell and molecular biology, biochemistry or biotechnology
  • Experiecne in analysing genome regulation, mRNA expression or protein levels.

Prefered qualifications

  • Biochemical or data analytical skills in deep-sequencing techniques (e.g. ChIP-seq, CUT & Run, RNA-seq, ATAC-seq).
  • Experience in mass spectorometry or genome editing (e.g. CRISPR, cloning).
  • Experience in analysing cellular responses or developmental processes

Selection

In order to succeed as a doctoral student at KTH you need to be goal oriented and persevering in your work. During the selection process, candidates will be assessed upon their ability to:

  • independently pursue his or her work
  • collaborate with others,
  • have a professional approach and
  • analyse and work with complex issues.

After the qualification requirements, great emphasis will be placed on personal competency.

Target degree: Doctoral degree

Information regarding admission and employment

Only those admitted to postgraduate education may be employed as a doctoral student. The total length of employment may not be longer than what corresponds to full-time doctoral education in four years ‘ time. An employed doctoral student can, to a limited extent (maximum 20%), perform certain tasks within their role, e.g. training and administration. A new position as a doctoral student is for a maximum of one year, and then the employment may be renewed for a maximum of two years at a time.

Application

Apply for the position and admission through KTH’s recruitment system. It is the applicant’s responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Other information

Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentAccording to agreement 
SalaryMonthly salary according to KTH’s doctoral student salary agreement
Number of positions1
Working hours100%
CitySolna
CountyStockholms län
CountrySweden
Reference numberC-2021-0161
ContactAnniina Vihervaara,
e-post: viher@kth.se
Published11.Mar.2021
Last application date30.Apr.2021 11:59 PM CET

Last updated: 2021-03-23

Content Responsible: David Gotthold(david.gotthold@scilifelab.se)