PhD student in Quantitative RNA Biology
Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University
Research at MBW experimentally addresses fundamental problems in molecular cell biology, integrative biology, and infection and immunobiology. State-of-the art and advanced methodologies are applied in a professional research environment characterized by its well-established international profile.
The Science for Life Laboratory (SciLifeLab) is a collaboration between four universities in Stockholm and Uppsala: Stockholm University, the Karolinska Institute, the Royal Institute of Technology, and Uppsala University. The SciLifeLab is a national centre for large-scale biosciences with a focus on health and environmental research. The centre combines advanced technical know-how and cutting-edge equipment with a broad knowledge in translational medicine and molecular biosciences.
Project description
This PhD student position is available in the laboratory headed by Associate Professor Marc Friedländer – part of the MBW Institute and located at the SciLifeLab. The group seeks to answer fundamental questions in RNA biology through quantitative approaches such as single-cell omics and new screening methods in combination with computational biology. Our group also has a research line on Paleotranscriptomics and has recently sequenced RNA from the extinct Tasmanian tiger.
The project revolves around our new agoTRIBE method, to experimentally map miRNA targets transcriptome-wide in single cells. The PhD student will computationally analyze single-cell data and integrate it with Omics data modalities to gain new insights into miRNA biology. The student will be working closely with wet-lab and dry-lab researchers in our team. Lab website: www.friedlanderlab.org.
Qualification requirements
In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.
In order to meet the specific entry requirements, the general syllabus for doctoral studies in the field of molecular biosciences stipulates that applicants mst have a completed university degree at an advanced level or at least 240 credits of university education (240 hp in the Swedish universities), including at least 120 hp at the bachelor level in molecular biology, biology, chemistry or similar subject. Candidates should have successfully completed courses at the advanced level in molecular biosciences or equivalent subject (at least 60 hp), of which at least 30 hp represent independent research project work. Candidates who have other documented qualifications, obtained in Sweden or elsewhere, that are judged to provide equivalent knowledge are also qualified.
The qualification requirements must be met by the deadline for applications.
Selection
The selection among the eligible candidates will be based on their capacity to benefit from the training. The following criteria will be used to assess this capacity: the candidates’ documented knowledge in a relevant field of research, written and oral proficiency in both Swedish and English, the capacity for analytical thinking, the ability to collaborate, as well as creativity, initiative, and independence. The candidate must have good programming/scripting skills. Previous experience with next-generation sequencing data, cancer biology or microRNA biology are advantages, but not required. The assessment will be based on previous experience and grades, the quality of the degree project, references, relevant experience, interviews, and the candidate’s written motivation for seeking the position.
Admission Regulations for Doctoral Studies at Stockholm University are available at: www.su.se/rules and regulations.
Contact
For more information, please contact Associate Professor Marc Friedländer, telephone: +46 737 12 15 58, marc.friedlander@scilifelab.se.
