Postdoc in Microfluidics for drug screening in 3D cell models
School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH
Job description
We now offer a Postdoctoral position in Microfluidics for drug screening centered on the development dropletmicrofluidics and related instrumentation for pharmaceuticals development with miniaturized 3D cell models at KTH Nanobiotechnology at the Science for Life Laboratory (SciLifeLab).The research group focuses on droplet microfluidics, 3D micro-tissue models and high-throughput screening.
The Biomicrofluidics group at KTH, together with pharma industry and academic partners aims to realize pre-clinical pharmaceuticals screening in miniaturized 3D cell models, to provide safer and more effective pharmaceutical drugs and reduce the need for animal drug testing. 3D micro-tissue models mimic the drug response from real tissue better than individual cells or 2D tissue models, but have not yet been produced at the scale needed for high-throughput screening. Key to this research project is the development of a microfluidic platform for minispheroids production and handling. The postdoctoral researcher will develop and test novel microfluidic instrumentation for minispheroid production, and deploy the microfluidic instrumentation platform with pharmaceutical industry and key academic partners, in Sweden, and abroad. The Postdoctoral researcher will primarily work at SciLifeLab Stockholm, but travel to our labs at AstraZeneca BioventureHub in Gothenburg is expected.
The successful candidate will work at the interface between microfluidics, tissue engineering, and drug screening, including:
- development and testing of 3D printed droplet microfluidic devices
- development instrumentation for large scale 3D micro-tissue production and handling
- characterization and validation of human 3D micro-tissue models with project partners
- deployment and evaluation of microfluidic instrumentation in industrial settings
- support innovation and ideas for grant proposals
What we offer
- A position at a leading technical university that generates knowledge and skills for a sustainable future.
- Engaged and ambitious colleagues along with a creative, international and dynamic working environment
- Work in Stockholm, in close proximity to nature
- An interdisciplinary and applied project in close collaboration with researchers from Karolinska Institutet and pharmaceutical industry partners.
- Help to relocate and be settled in Sweden and at KTH
Read more about what it is like to work at KTH
Qualifications
Requirements
- A doctoral degree or an equivalent foreign degree within a subject relevant to the position, e.g. Bioengineering, Biotechnology, Chemistry, Cell and molecular biology, Medical science, Electrical engineering, Mechanical engineering or Microfluidics. This eligibility requirement must be met no later than the time the employment decision is made.
- Research experience in applied microfluidics, life science instrumentation or related fields.
- The ability to express yourself very well in English, spoken and written, as this will be required in day-to-day work
Preferred qualifications
- A doctoral degree or an equivalent foreign degree, obtained within the last three years prior to the application deadline
- As a person, you have well-developed analytical and problem-solving skills and like to take responsibility.
- You are self-motivaded with a strong ability to take initiative and run projects.
- You have a strong collaboration skills including the ability to lead and to support research.
- You have a history of respectful and professional behaviour and attitudes in collaborative environment.
Great emphasis will be placed on personal skills.
Trade union representatives
You will find contact information to trade union representatives at KTH’s webbpage.
To apply for the position
Log into KTH’s recruitment system in order to apply for this position. You are the main responsible to ensure that your application is complete according to the ad.
The application must include:
- CV including relevant professional experience and knowledge.
- Copy of diplomas and grades from your previous university studies. Translations into English or Swedish if the original documents have not been issued in any of these languages.
- Brief account of why you want to conduct research, your academic interests and how they relate to your previous studies and future goals. Max two pages long.
Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).