Postdoctoral position in Rheumatology, Systemic Autoimmunity
Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 54,000 students, more than 7,500 employees and a turnover of around SEK 8 billion.
The Department of Medical Sciences is a large clinical institution with more than 250 employees and over 900 additional coworkers connected via the Uppsala University Hospital. The Department of Medical Sciences has a broad research profile with strong research groups in a number of different areas. The research carried out at the department is performed in close connection with the clinical activities at the Uppsala University Hospital, which includes both basic studies on the causes of a variety of illnesses and the development and evaluation of improved diagnostics and new treatment methods. More information about the Department of Medical Sciences can be found at www.medsci.uu.se
Within the Scandinavian Sjögren´s syndrome network, the goal is to identify novel risk genes, epigenetic changes and immunological mechanisms behind the development of primary Sjögren´s syndrome and its different clinical manifestations, particularly lymphoma. This is achieved by genome wide association studies (GWAS) and DNA sequencing. Further, we study epigenetic regulation through DNA methylation and gene expression in whole blood, sorted cells and single cells, as well as proteomics in sera. The duties consist of data analysis from GWAS, DNA methylation, DNA and RNA sequencing and proteomics.
PhD degree in medicine, molecular biology, molecular genetics, biomedicine or biotechnology or a foreign degree equivalent to a PhD degree in any of the subjects above. The degree needs to be obtained by the time of the decision of employment. Those who have obtained a PhD degree three years prior to the application deadline are primarily considered for the employment. The starting point of the three-year frame period is the application deadline. Due to special circumstances, the degree may have been obtained earlier. The three-year period can be extended due to circumstances such as sick leave, parental leave, duties in labour unions, etc.
Good knowledge in PLINK and R is required, as well as good oral and written skills in English. Personal qualities will be an important selection criterion, in particular the ability to collaborate with other researchers, take responsibility and work independently.
Experience with DNA- and RNA-preparation, PCR, library preparation for next generation sequencing and laboratory methods for isolation of different cell populations is meritorious. Knowledge about rheumatic diseases is an advantage.
About the employment
The employment is a temporary position of 2 years according to central collective agreement. Scope of employment 100 %. Starting date as agreed. Placement: Uppsala
For further information about the position, please contact: associate professor Gunnel Nordmark, 070-3134824 Gunnel.Nordmark@medsci.uu.se or researcher Juliana Imgenberg-Kreuz, 070-959 11 74 Juliana.Imgenberg@medsci.uu.se
Please submit your application by April 25 2023, UFV-PA 2023/1228.