Chemical Biology Consortium Sweden, CBCS, will from 2022 be a Swedish Research Council funded infrastructure of national interest. This means that the existing capabilities will be strengthened and new capabilities and four new nodes – at Lund, Uppsala, Linköping and Gothenburg Universities, respectively, will be established. CBCS (www.CBCS.se) has been in operation since 2010 with two nodes at KI and at Umeå University, respectively, and is an infrastructure for chemical biology at Science for Life Laboratory (www.scilifelab.se) in the Chemical Biology and Genome Engineering platform. CBCS offers services for the identification of chemical tools (bioactive small-molecules) for all fields of life sciences. The infrastructure offers collaborative service and guidance within assay development, small-molecule screening and hit to chemical probe optimization. Additional service offerings in small-molecule profiling, including Cell Painting, and screening in primary and complex disease models are currently being established.
The facility comprises Scilifelab Compound Center whose assignment is to serve the Swedish research community with distributing screening libraries on assay plates while preserving the quality of our collection. We also support precision medicine through functional testing in patient-near cells by endorse profiling of small molecules and disease models at single cell level and in patient-derived cells.The collection consists of over 200 000 chemical compounds and instrumentation includes a fully automated storage system; Liconic Kiwi ST-30 combined with a Bravo liquid dispensing system (Agilent) together with an acoustic liquid dispensing platform (Echo 550 & workstation) The collection is stored under environmentally controlled conditions and regular quality campaigns are performed to maintain the integrity of the collection.
We seek one individual within the fields of compound management and chemistry to join our team. The successful candidate will be part of an automation team and play a key role providing technical expertise in the creation of a national sample operation and expansion of capabilities to meet future needs of research. In this position you will work in a dynamic environment whilst supplying essential service to research projects across the academic world in Sweden. The work is highly collaborative, and you will join a team with collective responsibility for the overall delivery. The group has a strong emphasis on continuous improvement which you will contribute to in the form of individual and group projects.
We believe that you have the ability to be comfortable working at a fast pace with a goal orientated and team focused attitude. Possessing excellent communication skills with a dedicated and service minded approach is key. It is very important that you fully understand the drug discovery process and have technical proficiency along with necessary skills in chemistry, process engineering, QA and QC, automation solution development, instrument services, data management and information system development and support.
We expect you to be a positive, flexible person working in a clean and precise way. Interpersonal skills will be highly valued.
Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.
Welcome to apply at the latest 2022-01-16