Research Engineer to the Spatial Proteomics Infrastructure Unit
School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH
KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.
School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH) is one of the five schools of KTH and a strong constellation for research and education in the broader areas of health, environment, energy and materials. The School of Engineering Sciences in Chemistry, Biotechnology and Health conducts research and education in areas that cover several global challenges. Among them are the need of sustainable energy, health and aging population, climate change, sustainable production and working life, food production and clean water.
Science for Life Laboratory (SciLifeLab, http://www.scilifelab.se/) is a national center for large-scale life science research with an advanced technological infrastructure. At SciLifeLab, multidisciplinary research is carried out based on DNA sequencing, gene expression analysis, proteomics, bioinformatics, biostatistics and system biology. The goal is to enable Swedish researchers to analyze genes, transcripts and proteins in different organisms in order to map molecular mechanisms related to health and the environment. Examples of thematic research areas that are currently being processed within SciLifeLab are clinical genomics/proteomics, cancer genome and the genomics of complex diseases as well as ecological and environmental genomics.
The Spatial Proteomics Infrastructure Unit is part of the newly established Single Cell and Spatial Biology Platform and part of the research infrastructure at SciLifeLab. The platform is organized into different units that offers single cell and spatial omics technologies for detection of DNA, RNA, proteins and small molecules in cells and tissue sections. The focus of the Spatial Proteomics unit Cell Profiling – SciLifeLab is to offer highly multiplexed immunofluorescence using state of the art protocols and equipment, currently with the CODEX platform.
The team consist of three people today, including the Head of Unit, and is now looking for a fourth member to scale up and further develop its activities. The team works closely with the research group of Prof Emma Lundberg, and share labs and office space with her group of approximately 15 people.
In the role as research engineer in the Spatial Proteomics unit you will be working both in the lab and in the office. As a national unit, much work will be to perform projects for external users, but the position also include internal research and development. Wet lab work involves sample preparation of fresh frozen (FF) as well as formalin fixed paraffin embedded (FFPE) tissue sections, and to set-up instruments for image acquisition using fluorescence microscopy. Internal development projects can include optimizing and testing new protocols, conjugating and validating new antibodies for multiplexed immunofluorescence or developing integrated protocols together with other units of the Single Cell and Spatial Biology platform. Office work include image data processing and quality control, delivery of project reports and consultation with the users. Depending on the background and interest of the applicant, more time can be spent on image data analysis.
What we offer
- A position at a leading technical university that generates knowledge and skills for a sustainable future.
- Engaged and ambitious colleagues along with a creative, international and dynamic working environment
- Work in Stockholm, in close proximity to nature
- Help to relocate and get settled in Sweden and at KTH.
- A position that puts you in the centre of the strong and emerging research field of spatial omics, at the largest Swedish infrastructure for life science
- A graduate degree or an advanced level (higher education) in the research subject or equivalent competence, eg Bachelor of Science (BSc) in Life Science or equivalent.
- Experience from wet lab work with subject-related methods and professional skills.
- Excellent knowledge in English.
- Subject-related and professional skills
- Experience in microscopy, multiplexed imaging methods, tissue sample preparation and sectioning, antibody conjugation and antibody validation for immunofluorescence.
- Knowledge in histology, immunology, and/or quantitative image analysis and programming.
- Ph D level.
- Experience in other spatial technologies, such as in situ sequencing.
- Awareness of diversity and equal opportunity issues, with specific focus on gender equality.
As a person, you are reliable and a good team player that can also work independently and drive projects forward. You show problem-solving abilities and are technical. For this position it is also important to be organized, quality focused and service minded.
Great emphasis will be placed on personal competency.
Trade union representatives
You will find contact information to trade union representatives at KTH’s webbpage.
Log into KTH’s recruitment system in order to apply to this position. You are the main responsible to ensure that your application is complete according to the ad.
About the employment
The employment is valid for a limited time according to the agreement – for up to 24 months, with access according to agreement.
|Type of employment||Temporary position longer than 6 months|
|Contract type||Full time|
|First day of employment||According to agreement|
|Number of positions||1|
|Working hours||Heltid, 100%|
|Contact||Charlotte Stadler, email@example.com|
|Last application date||17.May.2021 11:59 PM CET|