School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH
KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.
School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH) is one of the five schools of KTH and a strong constellation for research and education in the broader areas of health, environment, energy and materials. The School of Engineering Sciences in Chemistry, Biotechnology and Health conducts research and education in areas that cover several global challenges. Among them are the need for sustainable energy, health and aging population, climate change, sustainable production and working life, food production and clean water.
The Cell profiling group (PI Emma Lundberg) at SciLifeLab in Stockholm works on different projects revolving around spatial proteomics for cells and tissues. The group consists of three teams: research, HPA production and the Spatial Proteomics facility, but the teams are interlinked and share a common infrastructure. We are now looking for one research engineer for the facility and one research engineer for the production team.
The production team produces and maintains the subcellular section of the Human Protein Atlas (HPA) with the aim to systematically map the location of all human proteins in cells, tissues and organs. As a research engineer in this team, you will be localizing proteins at the subcellular level in cell lines by using immunofluorescence (ICC-IF) and confocal microscopy. The tasks mainly include laboratory work, but also some analytical tasks. In the lab, you will mainly do cell cultivation, immunostaining and microscopy. The analytical tasks include qualitative image analysis and curation of data for the Cell Atlas. You will work according to established SOPs (Standard Operating Procedures) and document your work in LIMS (Laboratory Information Management System).
The Spatial Proteomics National Facility is part of the newly established Spatial and Single Cell Biology Platform and part of the research infrastructure at SciLifeLab. The focus of the Spatial Proteomics unit is to offer highly multiplexed immunofluorescence of cells and tissue sections. Currently we work with the latest instruments from Akoya Biosciences (Phenocyler Fusion) Lunaphore (COMET and LabSat). As a national facility, much work will be to perform service projects for external users, but the position also includes internal research and development, for eg validating new antibody panels and development of new methods and protocols. Depending on the background and interest of the applicant, more time can be spent on image data analysis.
What we offer
- A position at a leading technical university that generates knowledge and skills for a sustainable future
- Engaged and ambitious colleagues along with a creative, international and dynamic working environment
- Work in Stockholm, in close proximity to nature
- A position that puts you in the centre of the strong and emerging research field of spatial omics, at the largest Swedish infrastructure for Life Science
- Help to relocate and get settled in Sweden and at KTH.
- A graduate degree or an advanced level (higher education) in the research subject or equivalent competence, eg Bachelor of Science (BSc) in Life Science or equivalent
- Previous experience from wet lab work with subject-related methods and professional skills
- Excellent knowledge in English since this is neccessary in our daily work
- Awareness of diversity and equal opportunity issues, with specific focus on gender equality
- Great collaborative abilities and ability to work Independetly
Production team: Previous experience in laboratory work, including common methods in molecular biology, cell cultivation and immunostaining of cells (ICC-IF). It is a great advantage if you have experience of confocal microscopy and image analysis. Previous work with Tecan liquid handling robots and/or documentation with the help of a Laboratory Information Management System (LIMS) is also advantageous.
Spatial Proteomics facility: Previous experience in multiplexed imaging methods, tissue sample preparation including sectioning, antibody conjugation and antibody validation for immunofluorescence is a strong advantage. Also knowledge in immunology, histology, pathology and/or quantitative image analysis and programming is an advantage.
Great emphasis will be placed on personal competency. As a person, you are reliable and a good team player that can also work independently and drive projects forward. You have excellent communication skills. You are organized, well structured and thorough.
For the position in the facility it is extra important that you show problem-solving abilities and are technical. For this position it is also important to be organized, quality focused and service minded.
Trade union representatives
You will find contact information to trade union representatives at KTH’s webbpage.
Log into KTH’s recruitment system in order to apply to this position. You are responsible to ensure that your application is complete according to the instructions in the ad.
The application must include:
- CV including relevant professional experience and knowledge.
- Copy of diplomas and grades from your previous university studies. Translations into English or Swedish if the original documents have not been issued in any of these languages.
- Personal letter of why you apply for this position, your research interests and how they relate to your previous studies and future goals. Also write if you have more interest in any of the two positions. Max 1,5 pages long.
Your complete application must be received by KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).