The Integrated Structural Biology welcomes you to these two events. You can join either event – or both – and you can choose to participate online or on site in Air&Fire at SciLifeLab Campus Solna.

We invite you to either or both of our events:

• 3^rd Cryo-EM Facility National Meeting – December 13
• 1st Integrated Structural Biology platform user meeting – December 14

3^rd Cryo-EM Facility National Meeting

Welcome to join this meeting with users to discuss results and needs from the community.

Program – December 13

9.00	News from the Cryo-EM facility nodes in Stockholm and Umeå
10.00	Fika
10.20	PReSTO for Cryo-EM, Torben Rasmussen, Linköping
10.40	Chameleon sample preparation for cryo-EM, Sacha de Carlo, SPT Labtech
11:00	Recent advances in the field of CryoEM Gaurav Sharma, Thermo Fisher Scientific.
11:20	Structural proteomics for studying protein interactions and dynamics Simon Ekström, Lund University
11:40	Big and dynamic – An ancient and universal NMP kinase Tobias Sparrman
12:00	Lunch
13:00	Cryo-EM user discussion, previous in-person meeting (drop-in service, booking system, cryoScreeeNET) and sensing the interest for potentiating new applications (electron diffraction, FIB cryoET, cryo-CLEM)
15:00	Wrap-up
16:00	End of Meeting

1^st Integrated Structural Biology platform user meeting

The purpose of this meeting is to show complementary techniques available at SciLifeLab Infrastructure and to encourage interactions.

Program – December 14

8:45	General introduction to ISB platform
9.00	Presentation of Protein Production Sweden (PPS) Malin Bäckström
9.15	MicroED for structure determination of biomolecules,  Laura Pacoste, SU
9.35	NMR studies on VIM-2, Hermina Wieske, Uppsala University
9.55	Proteome-wide crosslinking mass spectrometry of host-pathogen interactions, Lotta Happonen, Lund University
10.15	Coffee Break
11.00	Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome, Luka Bacic, Uppsala University
11.20	Structural basis of DegP-protease temperature-dependent activation, Darius Šulskis, University of Gothenburg
11.40	The interface study of M1-protein and M1-specific IgG via structural mass spectrometry, TX-MS and HDX-MS, Di Tang, Lund University
12.00	Lunch
13.00	Cryo-EM structural study of the P5-type ATPases” Ping Li, Kopenhagen University, LU
13.20	Characterizing proteins in their native environment: Advances in in situ NMR, Johannes Thoma, University of Gothenburg
13.40	Unravelling the molecular basis of cell protection by Bcl-2 proteins, Gerhard Gröbner, Umeå University
14.00	Bruker on UF-MAS and structural biology
14.30	Discussion – user feed back
15.20	Final notes
15:30	End of Day

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