Omics Integration and Systems Biology – Online
February 8, 2023 @ 09:00 – February 10, 2023 @ 17:00 CET
The National Bioinformatics Infrastructure Sweden (NBIS) is pleased to announce the workshop in Omics Integration and Systems Biology. This workshop is open for PhD students, postdocs, group leaders and core facility staff from Swedish academic institutions looking for an introduction to multi-omics data analysis and integration of biological data. This course will include lectures and hands-on exercises from NBIS / Scilifelab experts from Stockholm, Lund and Gothenburg.
- Application opens: 15 December 2022
- Application closes: 25 January 2023
- Confirmation to accepted applicants: 1 February 2023
This online training event has no fee. However, if you accept a position at the workshop and do not participate (no-show) you will be invoiced 2000 SEK.
* Please note that NBIS cannot invoice individuals.
The aim of this course is to provide an integrated view of data-driven hypothesis generation through machine learning integration methods, biological graph / network analysis and genome-scale metabolic models. A general description of different methods for analyzing different omics data (e.g. transcriptomics and genomics) will be presented with some of the lectures discussing key methods and pitfalls in their integration. The techniques will be discussed in terms of their rationale and applicability. The course will also include hands-on sessions and seminars by invited speakers.
Some of the covered topics include:
- Data pre-processing and cleaning prior to integration;
- Application of machine learning for multi-omics analysis including deep learning;
- Multi-omics integration, clustering and dimensionality reduction;
- Biological network inference, community and topology analysis and visualization;
- Condition-specific and personalized modeling through Genome-scale Metabolic models for integration of transcriptomic, proteomic, metabolomic and fluxomig data;
- Identification of key biological functions and pathways;
- Identification of potential biomarkers and targetable genes through modeling and biological network analysis;
- Application of network approaches in meta-analyses;
- Similarity network fusion and matrix factorization techniques;
- Integrated data visualization techniques
Further details about the course content may be found on the course website.
This course is open for PhD students, postdocs, group leaders and core facility staff from Swedish academic institutions. Please note that NBIS training events do not provide any formal university credits. If formal credits are crucial, the student needs to confer with the home department before submitting a course application in order to establish whether the course is valid for formal credits or not.
Practical exercises can be performed using R or Python, so we only accept students with previous experience in one of those programming languages. We will not discuss how to process specific omics, and the students are referred to other NBIS courses for this matter.
- Basic knowledge in R or Python;
- Basic understanding of frequentist statistics;
- A computer with a web camera, Zoom, and permissions for installing software.
- Experience with analysis of NGS and other omic data;
- Completing NBIS courses “Introduction to Bioinformatics using NGS data” and “Introduction to biostatistics and machine learning”
- Basic conda and git knowledge
This workshop can accommodate a maximum of 25 participants. If we receive more applications, participants will be selected based on several criteria including entry requirements, motivation to attend the course as well as gender and geographical balance.
For questions about this workshop please contact: firstname.lastname@example.org