Clinical Genomics Stockholm

The Clinical Genomics Stockholm facility provides a dedicated research infrastructure for projects utilising massively parallel / next generation sequencing technologies. All projects are carried out in close collaboration with the Swedish healthcare system. The facility serves as a competence center assisting the translation of genomics-based tools to routine clinical care. All work is carried out in close collaboration with medical expertise provided by the clinical diagnostic laboratories and patients’ managing physicians. Also, the facility aims to improve the capacity of the public health microbiology for national surveillance of infectious diseases and for epidemic preparedness.

Services

• DNA sequencing.
  • DNA sequencing.Clinical exome sequencing
  • Clinical whole-genome sequencing
  • Microbial whole-genome sequencing
  • Targeted panels using various bait sets (contact for detailed information)
  • RNA Seq using both poly A and random priming
  • Ready-made libraries (prepared by collaborator)

Applications

• Large-scale analyses of the human genome and transcriptome, including targeted panels, exomes and whole genomes.
• Microbial analyses based on whole genome sequencing.

Current focus areas include inherited diseases, cancers and microbial surveillance applications. We are continuously looking for additional applications to expand the current focus areas.

Equipment

Library preparation

• Covaris E220 and S2 systems
• Agilent Bravo Configuration B systems
• Hamilton liquid handling systems
• Various systems for QC and quantification

Sequencing systems

• Illumina NovaSeq 6000
• Illumina HiSeq 2500
• Illumina iSeq

Using the facility

If you are interested in more information, please contact Valtteri Wirta (Head of facility).

Website

clinical.scilifelab.se

Open positions

Our current job openings can be found at SciLifeLab Vacancies section, or either at KI or KTH websites.

We encourage spontaneous applications, especially for bioinformatic or IT related positions.

We are also looking for motivated masters students in following areas: bioinformatics for rare inherited diseases, experimental wet lab work for cancer applications, bioinformatics and software development for cancer applications, and bioinformatics for microbial typing applications. Interested candidates are kindly requested to send in a CV and an application letter (free format) describing motivation as well as previously acquired key strengths. Please send material to valtteri.wirta@scilifelab.se