We are investigating the global and temporal changes of human microbiome in health and diseases. We develop computational and quantitative systems biology tools and models to understand the role of microbiome in host physiology and propose an improved microbiome-based personalized medicine pathway for future therapy. Construction of atlas of human microbiome and metagenome species is the main goal in the lab. We are updating different microbial gene catalogues together with metagenome species, including bacteria, fungi and phage to achieve better representation of uncultured genomes in the human microbiome. We characterize the metagenome species and gene catalogues with several functional annotations such antimicrobial resistance, virulence factors, mobile genetic elements, and secondary metabolites. Understanding the global relation between the human microbiome and antimicrobial resistance is one of the key questions we try to answer within the latest initiative of One Million Microbiome Project.
We are opening soon for postdoctoral research associate positions.