We investigate the dynamics of the extracellular matrix (ECM) and the cell–ECM crosstalk in lung health and disease. Utilizing advanced histological, transcriptomic, proteomic, and elemental analyses, we explore epithelial–mesenchymal niches in the lung and how they influence inflammation, tissue repair, and remodeling—processes central to chronic respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and bronchiolitis obliterans syndrome (BOS). Our research aims to contribute to the development of novel diagnostic markers and therapeutic strategies, ultimately improving outcomes for patients with debilitating pulmonary conditions.

Group Members:

Linda Elowsson
Arturo Ibáñez-Fonseca
Bryan Falcones
Anna Cederberg
Barbora Svobodová
Tom Delaire
Dimitrios Kalafatis