Novel method for identification of atherosclerosis biomarkers

Atherosclerosis can be developed for decades without any symptoms and when the disease becomes unstable myocardial infarction or stroke can be the first signs of the disease. Clinical tools like blood tests and image diagnostics are therefore required to improve prevention of myocardial infarction and stroke.

In a study involving several researchers at SciLifeLab as well as the Proteomics platform, a new biomarker for intraplaque hemorrhage and plaque instability has been identified. The novel translational approach applied for biomarker discovery in this study permits causal interpretation of candidates directly in relation to the underlying disease and paves the way for similar investigations in other vascular territories. The study was published in JACC: Basic to Translational Science.

Read full scientific paper in JACC: Basic to Translational Science.