There is a widespread misconception that white spotting in dogs has arisen as a by-product when we have selected for a tame behavior.
‘The main reason that dogs have various forms of white spotting is that we have deliberately chosen dogs with white spots for breeding’, says Leif Andersson, one of the researchers behind the study.
This has been the breeding practice for thousands of years, which is illustrated by the Roman authority on agriculture, Columella, who already around 100 AD described that shepherds preferred white sheep-herding dogs because they were easier to distinguish from wolves if they had to chase away wolves at dawn or dusk.
In the article, the researchers show that the white coat color in dogs is caused by mutations in the MITF gene that is crucial for normal development of pigment cells. The researchers show that these mutations do not affect the MITF protein but rather its genetic regulation.
‘These white markings occur not because the dogs cannot produce pigment but because they completely lack pigment cells in the skin in the areas that have white markings’, says Izabella Baranowska Körberg who obtained her PhD degree at SLU on a thesis in which this study was included.
‘As a result of the change in MITF gene regulation, not all pigment cells find their way to the dog’s skin during embryonic and fetal development. Since pigment cells also have an important function in the inner ear some dogs (5–15 per cent) with extreme white spotting as white boxers and Dalmatians are affected by impaired hearing or deafness’, says Göran Andersson who together with Leif Andersson led this research collaboration.
One of the researchers behind the article is Kerstin Lindblad-Toh, Co-Director of SciLifeLab.
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.