Alexander Suh

Key publications

Suh, A., Smeds, L., Ellegren, H. (2018) Abundant recent activity of retrovirus-like retrotransposons within and among flycatcher species implies a rich source of structural variation in songbird genomes. Molecular Ecology 27, 99–111.

Weissensteiner, M. H., Pang, A. W. C., Bunikis, I., Höijer, I., Vinnere-Petterson, O., Suh, A.*, Wolf, J. B. W.* (2017) Combination of short-read, long-read and optical mapping assemblies reveals large-scale tandem repeat arrays with population genetic implications. Genome Research 27, 697–708.

Kapusta, A., Suh, A., Feschotte, C. (2017) Dynamics of genome size evolution in birds and mammals. Proceedings of the National Academy of Sciences 114, E1460–E1469.

Suh, A., Witt, C. C., Menger, J., Sadanandan, K. R., Podsiadlowski, L., Gerth, M., Weigert, A., McGuire, J. A., Mudge, J., Edwards, S. V., Rheindt, F. E. (2016) Ancient horizontal transfers of retrotransposons between birds and ancestors of human pathogenic nematodes. Nature Communications 7, 11396.

Suh, A., Smeds, L., Ellegren, H. (2015) The dynamics of incomplete lineage sorting across the ancient adaptive radiation of neoavian birds. PLoS Biology 13, e1002224.

Research interests

The genome is a common feature of all cellular organisms and contains a comprehensive record of evolution. At a closer look, the genome is in fact a ‘genomic microcosm’ – a smörgåsbord of interactions among/between host genes and parasitic genes, such as transposons and viruses.

We study how these genomic parasites impact genome structure and speciation of birds, crocodilians, and parasitic nematodes. Beware, some of these jumping genes even jump between genomes!

Ongoing research revolves around the evolution of birds, crocodilians, and parasitic nematodes, however, our interests are not limited to a specific group of organisms. We aim at understanding biodiversity both on the level of cellular organisms and on the level of transposons and viruses, as well as the interactions between these genomic parasites and their hosts’ genomes or transcriptomes.

Our long-term scientific goals are to shed light on the following three main research questions:

  1. How do the highly diverse ‘genomic microcosms’ of transposons and viruses influence the diversification of their animal hosts?
  2. How are interactions between or among hosts and parasites manifested on recent and deep timescales of genome evolution?
  3. How much do we really know about the complexity of animal genomes and how much of it remains genomic ‘dark matter’?

 

Group members

Anne-Marie Dion-Côté, post doc
Valentina Peona, PhD student

Contact

alexander.suh@ebc.uu.se

Last updated: 2022-11-30

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