The group focuses on mapping and modulating protein function in human gut microbiome species. We want to understand how drugs act, how species metabolize complex carbohydrates, and to map how the species of the microbiome interact with each other physically or via metabolites. Our goal is to be able to manipulate the gut microbial community using drugs or diet to promote a healthy state. We use systems biology approaches based on proteomics.
André Mateus
Umeå University
Key Publications
Dual screen for gut metabolites suppressing enterobacterial growth and invasiveness reveals structure–activity relationships among anti-infective indoles
Gut Microbes, 2026
Mitochondrial dysfunction in muscle cells induced by snoring vibrations
Mitochondrion, 2026
Identification of drug repurposing candidates for the treatment of polycystic kidney disease
British Journal of Pharmacology, 2026