induced Pluripotent Stem Cell (iPSC) is a unique cell type due to its ability to expand massively, long-term stored maintaining its ability to differentiate into all cell types of the human body. Thus, iPSCs are optimal for creating cellular models of human organs and for deriving cell therapies to replace dead or injured cell. iPSC can be established from human skin of any individual, the intact genome is maintained and if specific genes are to be studied CRISPR editing of iPSC is powerful.
Anna Falk
Lund University
Keywords
Key Publications
The Advanced Therapies model of Lund an integrated approach to accelerate access for many patients
Molecular Therapy Methods & Clinical Development, 2025
Heparan sulfate N-deacetylase/N-sulfotransferase-1 regulates glioblastoma cell migration and invasion
Matrix Biology, 2025
Defined culture conditions robustly maintain human stem cell pluripotency, highlighting a role for Ca2+ signaling
Communications Biology, 2025