Our Unit is dedicated to advancing spatial biology and multi-omics research through innovative, state-of-the-art spatial transcriptomics technologies. Our mission is to provide spatial transcriptomics data in tissues to understand the spatial organization of biological systems, cell behavior, and disease mechanisms across various research fields, from basic research to clinical studies.
Chika Yokota
Key publications
Kukanja P, Langseth CM, Rubio Rodríguez-Kirby LA, Agirre E, Zheng C, Raman A, Yokota C, Avenel C, Tiklová K, Guerreiro-Cacais AO, Olsson T, Hilscher MM, Nilsson M, Castelo-Branco G.
Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology.
Cell. 2024 Apr 11;187(8):1990-2009.e19. doi: 10.1016/j.cell.2024.02.030. Epub 2024 Mar 20. PMID: 38513664
Floriddia EM, Lourenço T, Zhang S, van Bruggen D, Hilscher MM, Kukanja P, Gonçalves Dos Santos JP, Altınkök M, Yokota C, Llorens-Bobadilla E, Mulinyawe SB, Grãos M, Sun LO, Frisén J, Nilsson M, Castelo-Branco G.
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury.
Nat Commun. 2020 Nov 17;11(1):5860. doi: 10.1038/s41467-020-19453-x. PMID: 33203872
Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Häring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I.
Spatiotemporal structure of cell fate decisions in murine neural crest.
Science. 2019 Jun 7;364(6444):eaas9536. doi: 10.1126/science.aas9536. PMID: 31171666