Claudia Fredolini


Head of Affinity Proteomics-Stockholm Co-Director and Coordinator Clinical Proteomics and Immunology Platform

Key publications

Microfluidic Device for Patient-Centric Multiplexed Assays with Readout in Centralized Laboratories
Janosch Hauser
Matilda DaleOlof BeckJochen M SchwenkGöran StemmeClaudia Fredolini, Niclas Roxhed
Anal Chem. 2023 Jan 17;95(2):1350-1358. doi: 10.1021/acs.analchem.2c04318. Epub 2022 Dec 22. PMID: 36548393; PMCID: PMC9850402.


Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.
Roxhed N, Bendes A, Dale M, Mattsson C, Hanke L, Dodig-Crnković T, Christian M, Meineke B, Elsässer S, Andréll J, Havervall S, Thålin C, Eklund C, Dillner J, Beck O, Thomas CE, McInerney G, Hong MG, Murrell B, Fredolini C, Schwenk JM.
Nat Commun. 2021 Jun 17;12(1):3695. doi: 10.1038/s41467-021-23893-4.

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.
Zeybel M, Altay O, Arif M, Li X, Yang H, Fredolini C, Akyildiz M, Saglam B, Gonenli MG, Ural D, Kim W, Schwenk JM, Zhang C, Shoaie S, Nielsen J, Uhlén M, Borén J, Mardinoglu A.
Mol Syst Biol. 2021 Oct;17(10):e10459. doi: 10.15252/msb.202110459.

Microfluid Device and Method thereof for assays in samples from mammals (on-chip immunoassay)
Inventors: Niclas Roxhed, Bonsens AB, Claudia Fredolini, Janosch Hauser
Patent application number at Swedish Patent and registration office (PRV): 2130266-6

Precise blood proteome profiling in an undiagnosed population with COVID-19. 
Claudia Fredolini, Tea Dodig-Crnković, Annika Bendes, Leo Dahl Matilda Dale, Cecilia Mattsson, Cecilia E Thomas, Olof Beck, Niclas Roxhed and Jochen M Schwenk. (Pre-Print on Medrxiv and under revision ).

Bead-Based Assays for Validating Proteomic Profiles in Body Fluids
Bendes A, Dale M, Mattsson C, Dodig-Crnković T, Iglesias MJ, Schwenk JM, Fredolini C.
Methods Mol Biol. 2021;2344:65-78. doi: 10.1007/978-1-0716-1562-1_5.”

Claudia Fredolini

Research Interest

The Affinity Proteomics Units-Stockholm collaborates with clinical researchers’ providing expertise and state-of-the art technologies for protein profiling and quantification.
Our main focus is on discovery, verification and validation of biomarkers in body fluids.
Our lab is equipped with a number of robust commercial platforms enabling high-throughput, high-multiplex protein quantification, however, we are also engaged in research and development of new methods including multiplex assays for the validation of new panels of candidate biomarkers (not commercially available) and low invasive micro sampling strategies to enable large population studies and monitoring of biomarkers.

Group Members

Matilda Dale
Maryam Sahi
Sarah Andersson

Last updated: 2023-12-08

Content Responsible: David Gotthold(