Focusing on psychoneurobiology, activities of the group include:
- research on the molecular underpinnings of gonadal hormones´ influence on women’s behaviour and mental health; by employing genetic, endocrine, pharmacological, neurophysiological and neuroimaging measures, we aim to characterize diagnosis- and treatment-related biomarkers of sex-specific disorders.
- research on the effects of early-life stress and alcohol exposure on brain and behaviour; (epi)gene-environment interactions are investigated in rodents as well as human population-based samples, with special focus on adolescence, to identify biomarkers of vulnerability to alcohol use and misuse.
Erika Comasco, Associate professor
Manon Dubol, postdoc
Julia Breedh, PhD student
Maria Vrettou, PhD student
Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans. Nylander I, Todkar A, Granholm L, Vrettou M, Bendre M, Boon W, Andershed H, Tuvblad C, Nilsson KW, Comasco E. Molecular Neurobiology. 2017 Oct;54(8):6225-6234.
Supraphysiological Hormonal Status, Anxiety Disorders, and COMT Val/Val Genotype are Associated with Reduced Sensorimotor Gating in Women. Comasco E, Hellgren C, Olivier J, Skalkidou A, Sundström Poromaa I. Psychoneuroendocrinology. 2015 Oct; 60:217-23.
Emotional Fronto-Cingulate Cortex Activation and Brain Derived Neurotrophic Factor Polymorphism in Premenstrual Dysphoric Disorder. Comasco E, Hahn A, Ganger S, Gingnell M, Bannbers E, Oreland L, Wikström J, Epperson CN, Lanzenberger R, Sundström-Poromaa I. Human Brain Mapping. 2014 Sep;35(9):4450-8.
View more here: https://www.ncbi.nlm.nih.gov/pubmed/?term=comasco+e