Gerhard Gröbner

Key publications

Domain specific insight into the recognition of BH3-death motifs by the pro-survival Bcl-2 protein
Ameeq Ul Mushtaq, Jörgen Ådén, Katan Ali, and Gerhard Gröbner
Biophysical Journal 121 (2022) 4517-4525

Neutron reflectometry and NMR spectroscopy of full length Bcl-2 protein reveal its membrane localization and conformation
Ameeq Ul Mushtaq, Jörgen Åden, Luke Clifton, B. Hanna Wacklin, Mario Campana, Artur P.G. Dingeldein, Cecilia Persson, Tobias Sparrman and Gerhard Gröbner
Communications Biology 4 (2021) 507

Comprehensive metabolomics analysis of PC tissue in relation to tumor aggressiveness and TMPRSS2-ERG fusion status
Ilona Dudka, Elin Thysell, Kristina Lundquist, Henrik Antti, Diego Iglesias-Gato, Amilcar Flores-Morales, Anders Bergh, Pernilla Wikström and Gerhard Gröbner
BMC Cancer 20-437 (2020) 1-17

Two Types of Alzheimer’s beta-amyloid (1-40) Peptide Membrane Interactions: Aggregation Preventing Transmembrane Anchoring Versus Accelerated Surface Fibril Formation
Marcus Bokvist, Fredrick Lindström, Anthony Watts and Gerhard Gröbner
Journal of Molecular Biology 335 (2004) 1039 – 1049

Observation of Light-induced Structural Changes of Retinal within Rodopsin
Gerhard Gröbner, Ian Burnett, Clemens Glaubitz, Gregory Choi, James Mason, Anthony Watts
Nature 405 (2000) 810 – 813

Virtually every biological process proceeds via membranes and their constituents. However, understanding the function of these biological membranes – ranging from basic features of their lipid matrix to the complex activity of its proteins – is one of the most challenging tasks in the life sciences. In our research we unravel the function of mitochondrial membranes by providing atomic level insight into their molecular organization by using advanced liquid and solid-state Bio-NMR approaches and neutron scattering techniques (ESS). In particular, we are unravelling in the interplay of the Bcl-2 protein family with mitochondrial membrane system to regulate programmed cell death.

Group members

Jörgen Åden
Ilona Dudka
Tamas Nagy
Sergiy Borodin

Last updated: 2023-03-28

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