Janne Lehtiö

Stratmann S, Vesterlund M, Umer HM, Eshtad S, Skaftason A, Herlin MK, Sundström C, Eriksson A, Höglund M, Palle J, Abrahamsson J, Jahnukainen K, Munthe-Kaas MC, Zeller B, Tamm KP, Lindskog C, Cavelier L, Lehtiö J, Holmfeldt L. Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children. Leukemia 2023 Mar;37(3):550-559. https://doi.org/10.1038/s41375-022-01796-7

Babačić H, Christ W, Araújo JE, Mermelekas G, Sharma N, Tynell J, García M, Varnaite R, Asgeirsson H, Glans H, Lehtiö J, Gredmark-Russ S, Klingström J, Pernemalm M., Comprehensive proteomics and meta-analysis of COVID-19 host respons. Nature Comm 2023, 14, 5921. https://doi.org/10.1038/s41467-023-41159-z

Herbst SA*, Vesterlund M*, Helmboldt AJ, Jafari R, Siavelis I, Stahl M, Schitter EC, Liebers N, Brinkmann BJ, Czernilofsky F, Roider T, Bruch PM, Iskar M, Kittai A, Huang Y, Lu J, Richter S, Mermelekas G, Umer HM, Knoll M, Kolb C, Lenze A, Cao, Österholm C, Wahnschaffe L, Herling C, Scheinost S, Ganzinger M, Mansouri L, Kriegsmann K, Kriegsmann M, Anders S, Zapatka M, Del Poeta G, Zucchetto A, Bomben R, Gattei V, Dreger P, Woyach J, Herling M, Müller-Tidow C, Rosenquist R, Stilgenbauer S, Zenz T, Huber W, Tausch E, Lehtiö J^§ and Dietrich D^§. Proteogenomics refines the molecular classification of chronic lymphocytic leukemia. Nature Comm. 2022 Oct 20;13(1):6226 (§ shared last author). https://doi.org/10.1038/s41467-022-33385-8

Tamborero D, Dienstmann R, Rachid M.J, Boekel J, Lopez-Fernandez A, Jonsson M,  Razzak A, Braña I, De Petris L, Yachnin J, Baird RD, Loriot Y, Massard C, Martin-Romano P, Opdam F, Schlenk RF, Vernieri C, Masucci M, Villalobos X, Chavarria E, Cancer Core Europe consortium, Balmaña J, Apolone G, Caldas C, Bergh J, Ernberg I, Fröhling S, Garralda E, Karlsson C, Tabernero J, Voest E, Rodon J, Lehtiö J. The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology. Nature Cancer 2022, Feb;3(2):251-261. https://doi.org/10.1038/s43018-022-00332-x

Lehtiö J*, Arslan T, Siavelis I, Pan Y, Socciarelli F, Berkovska O, Umer HM, Mermelekas G,  Pirmoradian M, Jönsson M, Brunnström H, Brustugun OT, Pinganksha Purohit K , Cunningham R, Foroughi H, Isaksson S, Arbajian E, Aine M, Karlsson A, Kotevska M, Hansen CG, Drageset Haakensen V, Helland Å, Tamborero D, Johansson HJ, Branca RMM, Planck M, Staaf J,  Orre LM. Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms. Nature Cancer, 2021Nov;2(11):1224-1242. (*corresponding author) https://doi.org/10.1038/s43018-021-00259-9

Tamborero D, Dienstmann R, Rachid MH, Boekel J, Baird R, Braña I, De Petris L, Yachnin J, Massard C, Opdam FL, Schlenk R, Vernieri C, Garralda E, Masucci M, Villalobos X, Chavarria E; Cancer Core Europe consortium, Calvo F, Fröhling S, Eggermont A, Apolone G, Voest EE, Caldas C, Tabernero J, Ernberg I, Rodon J, Lehtiö J. Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal. Nature Medicine. 2020 Jul;26(7):992-994. https://doi.org/10.1038/s41591-020-0969-2

Johansson HJ, Socciarelli F, Vacanti NM, Haugen MH, Zhu Y, Siavelis I, Fernandez A, Aure MR, Sennblad B, Vesterlund M, Branca RM, Orre LM, Huss M, Fredlund E, Beraki E, Garred Ø, Boekel J, Sauer T, Zhao W, Nord S, Höglander EK, Jans CD, Brismar H, Haukaas TH, Bathen TF, Schlichting E, Naume B, OSBREAC, Luders T, Borgen E, Kristensen VN, Russnes HG, Lingjærde OC, Mills GB, Sahlberg KK, Børresen-Dale A.L, Lehtiö J., Breast cancer quantitative proteome and proteogenomic landscape. Nature Comm, 10 Apr, 2019. https://doi.org/10.1038/s41467-019-09018-y

Orre LM, Vesterlund M, Pan Y, Arslan T,  Zhu Y, Fernandez Woodbridge A, Frings O, Fredlund E, Lehtiö J. SubCellBarCode: Proteome-wide mapping of protein localization and relocalization. Molecular Cell. 2019 Jan 3. https://doi.org/10.1016/j.molcel.2018.11.035

Zhu Y, Orre LM, Johansson HJ, Huss M, Boekel J, Vesterlund M, Fernandez-Woodbridge A, Branca RMM, Lehtiö J. Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow. Nature Commun. 2018 Mar 2;9(1):903. https://doi.org/10.1038/s41467-018-03311-y