Jessica Nordlund

Platform Scientific Director: Genomics, Uppsala University

Bluesky

Jessica.Nordlund@medsci.uu.se

Keywords

childhood cancer, drug screening, Epigenomics, genetics, genomics, leukemia, Single-cell, spatial, transcriptomics

Key Publications

Gezelius H, Enblad AP, Lundmark A, Åberg M, Blom K, Rudfeldt J, Raine A, Harila A, Rendo V, Heinäniemi M, Andersson C, Nordlund J+. Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening. NAR Genom Bioinform. 2024 Mar;6(1):lqae001. https://doi.org/10.1093/nargab/lqae001

Lysenkova Wiklander M, Arvidsson G, Bunikis I, Lundmark A, Raine A, Marincevic-Zuniga Y, Gezelius H, Bremer A, Feuk L, Ameur A, Nordlund J+. A multiomic characterization of the leukemia cell line REH using short- and long-read sequencing. Life Sci Alliance. 2024 7(8):e202302481. https://doi.org/10.26508/lsa.202302481

Krali O, Marincevic-Zuniga Y, Arvidsson G, … Nordlund J+. Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia. NPJ Precis Oncol. 2023 Dec 8;7(1):131. https://doi.org/10.1038/s41698-023-00479-5

Foox J, Nordlund J, … Mason CE (2021) The SEQC2 epigenomics quality control (EpiQC) study. Genome Biology 22(1). https://doi.org/10.1186/s13059-021-02529-2

Raine, A., Manlig, E., Wahlberg, P., Syvänen, A.-C., & Nordlund, J. (2017). SPlinted Ligation Adapter Tagging (SPLAT), a novel library preparation method for whole genome bisulphite sequencing. Nucleic Acids Research, 45(6), e36–e36. https://doi.org/10.1093/nar/gkw1110

SciLifeLab / Contact / Jessica Nordlund

We develop and apply cutting-edge molecular approaches to analyze the genomes, transcriptomes, epigenomes, and proteomes of clinical samples. By integrating multi-omics data with machine learning, we aim to identify biomarkers that distinguish individual patients from others with similar clinical features, refine molecular diagnoses, and uncover novel therapeutic strategies.

As Managing Director of the Genomics Platform, I have a strong interest in emerging technologies and innovative applications across the genomics field, with a focus on driving their translation into research as well as clinical settings.

Group Members:

Amanda Raine, Senior Researcher
Henrik Gezelius, Researcher
Anders Lundmark, Bioinformatician
Maria Globisch, Post doc
Birong Zhang, Post doc
Dea Gogishvili, Post doc
Olga Krali, PhD student
Mariya Lysenkova Wiklander, PhD student
Anna Pia Enblad, PhD student

Last updated: 2025-05-12

Content Responsible: David Gotthold(david.gotthold@scilifelab.se)