I study molecular mechanisms of positive-sense RNA virus replication. In this work, my group resides at the intersection of molecular virology, structural biology and membrane trafficking. Our research often has a strong component of cryo-EM, in particular cryo-electron tomography of cells and tissues. In this work, we rely heavily on Umeå Centre for Electron Micrsocopy, a SciLifeLab national facility for cryo-EM.
Lars-Anders Carlson
Umeå University
Keywords
Key Publications
Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation
Nature Communications, 2026
Illuminating druggable dark matter in RNA virus replication using in situ cryo-EM
Current Opinion in Virology, 2025
The ACBD3 protein coordinates ER-Golgi contacts to enable productive TBEV infection
Journal of Virology, 2025
Flotation Assay With Fluorescence Readout to Study Membrane Association of the Enteroviral Peripheral Membrane Protein 2C
BIO-PROTOCOL, 2025
Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in <i>Giardia intestinalis</i>
Nucleic Acids Research, 2024