The research by Lena Eliasson aims to understand the pathogenesis of diabetes. She investigates cellular mechanisms underlying impaired insulin- and glucagon-secretion from pancreatic islet β- and α-cells, respectively. The focus is on single cell physiology and molecular biology involving studies of ion-channels, exocytosis and miRNA-mRNA-protein networks important in the regulation of islet cell function.
Lena Eliasson
Lund University
Key Publications
Dynamic changes in circulating microRNAs during oral glucose tolerance testing support their potential as diagnostic and monitoring biomarkers in cystic fibrosis-related diabetes
Diabetologia, 2026
Network-based insights into miRNA regulation of β-cell insulin secretion in type 2 diabetes
iScience, 2025
Single Fusion Pore Analysis via Single Cell Amperometry Uncovers Impaired Pore Expansion That Restricts Insulin Exocytosis in Human Type 2 Diabetes
Angewandte Chemie International Edition, 2025
HMGCR and rosuvastatin regulates GLP-1 secretion and expression – a translational study
The Journal of clinical endocrinology and metabolism, 2025
Single Fusion Pore Analysis via Single Cell Amperometry Uncovers Impaired Pore Expansion That Restricts Insulin Exocytosis in Human Type 2 Diabetes
Angewandte Chemie, 2025