The research by Lena Eliasson aims to understand the pathogenesis of diabetes. She investigates cellular mechanisms underlying impaired insulin- and glucagon-secretion from pancreatic islet β- and α-cells, respectively. The focus is on single cell physiology and molecular biology involving studies of ion-channels, exocytosis and miRNA-mRNA-protein networks important in the regulation of islet cell function.
Lena Eliasson
Lund University
Key Publications
Potential Utility of Circulating MicroRNA-483 as a Biomarker for IGF-II–Associated Non–Islet Cell Tumor Hypoglycemia
The Journal of Clinical Endocrinology & Metabolism, 2024
Apolipoprotein A-I priming via SR-BI and ABCA1 receptor binding upregulates mitochondrial metabolism to promote insulin secretion in INS-1E cells
PLoS ONE, 2024
IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
iScience, 2024
IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
Mendeley Data, 2024
IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
Mendeley Data, 2024