Mafalda Sousa Ferreira

Key Publications
Seasonal camouflage as a model to understand the scope for rapid adaptation in a changing world
2026
The long noncoding RNA VIM-AS1 and nucleoporin Nup358/RanBP2 regulate SMAD nuclear accumulation during TGF-β signaling
Nucleic Acids Research, 2026
Adaptive introgression from Pacific herring to Atlantic herring in the brackish Baltic Sea
2025
Evolution of complexity through regulatory variation at a single gene
Proceedings of the National Academy of Sciences, 2025
The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring
Nature Communications, 2024

Research interests

Our group focus on understanding the evolution and molecular basis of adaptive traits. In particular, we are interested in how species adapt to seasonal environments by undergoing seasonal changes in phenotype, also known as phenologies. We study populations in their natural settings and in museum collections. We use comparative genomics and population genomics to understand how seasonal traits have evolved in closely related groups of species and within populations. We also use genomics to study which genes underly variation in within season trait variation (ex. variation in winter phenotype). Using both historic and modern datasets, we ask questions regarding how genetic variation linked to phenotypic variation has allowed species to adapt to recent climate change. With functional genomic techniques, we study the molecular mechanism that allow alternation of phenotype between seasons and how this mechanism is controlled by external environmental factors, including photoperiod and temperature. Finally, we are interested in using the link between genotype, phenotype and environment to guide the conservation of species inhabiting seasonal environments.

Current models studied in the lab include species of hares, ptarmigans and grouse and their ability to alternate color between summer and winter.

Group Members

Huijuan Bi, Researcher
Maja Svedberg, PhD Student

Last updated: 2025-09-29

Content Responsible: David Gotthold(david.gotthold@scilifelab.se)