SciLifeLab

Maria Tenje

Maria Tenje
Uppsala University

Research interests

The EMBLA group is led by Dr. Maria Tenje and comprises researchers with backgrounds in material science, nanotechnology, chemistry and physics. EMBLA is short for Exploring Microtechnology for Biomedical and Life science Applications and our research is focused on translating microsystems and microfluidic solutions to applications within the life sciences. Especially, we focus on organs-on-chip and droplet-based microfluidics.

We are located at the Ångström Laboratory at Uppsala University. I also have affiliation with the Department of Biomedical Engineering at Lund University and parts of my research group are located there. At Uppsala and have direct access to the state-of-the-art clean room facilities MSL that are part of the Swedish research infrastructure Myfab with 2.000 m² advanced equipment for fabrication and characterisation of micro- and nanostructures. These facilities are the important basis of our research.

Since 2016 we also lead a pilot facility within SciLifeLab called Customized Microfluidics. Our mission is to advance Swedish life science research by providing support in design and fabrication of microfluidic systems customized for your specific research needs. Our service is free of charge to researchers at all Swedish universities. For more information and contact details, please visit http://www.teknik.uu.se/microsystems-technology+/customizedmicrofluidics-en/

Group members

Maria Tenje – PI
Gemma Mestres – Senior Researcher
Mathias Ohlin – Postdoc
Anette Wolff – PhD student
Anna Fornell – PhD student
Frida Sjögren – PhD student
Ana María Porras – PhD student
Krishna Narayan – MSc studnet
Karolina Svensson – MSc student
Emma Thomée – MSc student

Key publications

Andersson, Q. JIa, A. Abella, X-Y. Lee, M. Landreh, P. Purhonen, H. Hebert, M. Tenje, C.V. Robinson, Q. Meng, G.R. Plaza, J. Johansson, A. Rising. Biomimetic spinning of artificial spider silk from chimeric minispidroin, Nature Chemical Biology 13 (2017) 262-264
Mestres, A. Wolff, J. Hilborn, M. Tenje. Microfluidic system with integrated 3D cell culture matrix – towards more in vivo-like organ-on-chip models, European Cells and Materials 31 (supp. 1) (2016) 229

A. Fornell, J. Nilsson, L. Jonsson, P. Periyannan Rajeswari, H. N. Joensson, M. Tenje. Controlled lateral positioning of microparticles inside droplets using acoustophoresis, Analytical Chemistry 87(20) (2015) 10521-105426
Wolff, M. Antfolk, B. Brodin, M. Tenje. In vitro blood-brain barrier models – an overview of established models and new microfluidic approaches, Journal of Pharmaceutical Sciences, Vol 104 pp. 2727-2746 (2015)
M. Fischer, C. Pedersen, K. Elkjær, N.N. Noeth, S. Dohn, A. Boisen, M. Tenje. Development of a microfabricated electrochemical-cantilever hybrid platform, Sensors and Actuators B: Chemical 157(1) (2011) 321-327