In the Data-Driven Determination of Macromolecular Structures (D3MS) group, we develop new experimental and computational approaches to unravel the subtleties of protein structures and achieve unprecendented levels of detail in macromolecular models.
We use a variety of computational and experimental approaches, from mathematical models to machine learning, and from crystallography to cryoEM. We use these tools to design new ways of determining macromolecular structures that reveals more about how they function.
What connects all of our methods is the idea that decisions should be driven by the data.
We are part of the bioinformatics division at Linköping University. In addition to our SciLifeLab affiliation through the DDLS program, we are part of the Wallenberg Centre for Molecular Medicine (WCMM) at Linköping.