Karampelias C, Liu K-C, Tengholm A, Andersson O.
Mechanistic insights and approaches for β-cell regeneration.
Nature Chemical Biology. 2025
DOI: 10.1038/s41589-024-01822-y
Mi J, Liu KC, Andersson O.
Decoding pancreatic endocrine cell differentiation and beta-cell regeneration in zebrafish.
Science Advances. 2023 Aug 18;9(33):eadf5142.
Chu L, Terasaki M, Mattsson C, Teinturier R, Charbord J, Dirice E, Liu KC, Miskelly MG, Zhou Q, Wierup N, Kulkarni RN, Andersson O.
In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system.
Cell Chemical Biology. 2022 Sep 15;29(9):1368-1380.
Karampelias C, Watt K, Mattsson CL, Ruiz ÁF, Rezanejad H, Mi J, Liu X, Chu L, Locasale JW, Korbutt GS, Rovira M, Larsson O, Andersson O.
MNK2 deficiency potentiates β-cell regeneration via translational regulation.
Nature Chemical Biology. 2022 Sep;18(9):942-953.
Karampelias C, Rezanejad H, Rosco M, Duan L, Lu J, Pazzagli L, Bertolino P, Cesta CE, Liu X, Korbutt G, Andersson O.
Reinforcing one-carbon metabolism via folic acid/Folr1 promotes beta-cell differentiation.
Nature Communications. 2021 Jun 7;12(1):3362.
Charbord J, Ren L, Sharma RB, Johansson A, Ågren R, Lianhe Chu L, Tworus D, Schulz N, Charbord P, Stewart AF, Wang P, Alonso LC, Andersson O.
In vivo screen identifies a SIK inhibitor that induces β-cell proliferation through a transient UPR.
Nature Metabolism. 2021 May;3(5):682-700.
