Key publications

Examples of recent publications that team members have co-authored as a result of support to user projects:

Hafstað et al. Regulatory networks and 5′ partner usage of miRNA host gene fusions in breast cancer. Int J Cancer 151:95-106 (2022).

Kierczak et al. Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability. Nat Commun 13:2532 (2022).

Stratmann et al. Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression. Blood Adv 6:152-164 (2022)

Yang et al. Novel loss-of-function variant in DENND5A impedes melanosomal cargo transport and predisposes to familial cutaneous melanoma. Genet Med 24:157-169 (2022)

Zheleznyakova et al. Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology. Proc Natl Acad Sci USA 118:e2011574118 (2021)

Pär Engström

The National Bioinformatics Infrastructure Sweden (NBIS) constitutes the SciLifeLab Bioinformatics platform and forms the Swedish node in ELIXIR (the European infrastructure for biological information). NBIS is a distributed infrastructure with staff at six sites (Göteborg, Linköping, Lund, Stockholm, Uppsala, and Umeå), providing a range of services to support life sciences in Sweden. NBIS supports both research groups not having their own bioinformatics resources and large established research groups with their own bioinformaticians needing specialised expertise.

The vision and mission of NBIS is to enable world-class life science research and maximise scientific and societal impact of collected data by:

  • Providing expert knowledge, innovative data integration, advanced training, efficient data publication for open science, and access to high-performance data analysis methods
  • Coordinating bioinformatics support within Sweden and making bioinformatics easily accessible for life science researchers
  • Swiftly responding to changes in support needs as new techniques are developed and utilised
  • Forming the Swedish ELIXIR node and participating in relevant international projects

I lead a team within NBIS focusing on support to health and clinical research. Besides Stockholm, the team has members in Uppsala, Linköping and Lund, and is jointly managed by me and Bengt Sennblad (SciLifeLab Uppsala).

For information about the services offered by NBIS, please see the NBIS web site.

Pär leads the Bioinformatics Long-term Support (WABI) team within the SciLifeLab Bioinformatics Platform (NBIS), together with Björn Nystedt and Thomas Svensson.

Last updated: 2023-08-10

Content Responsible: David Gotthold(