Pontus Nordenfelt
The Nordenfelt Lab is interested in the interplay between human cells and their environment and the cell biology that controls the outcome of the interactions. This could be immune cells trying to find their way to invading bacteria and viruses or cancer cells migrating out of a tumor. Surface molecules, morphology, and biomechanical forces govern these interactions. Antibodies, the complement system, and the cellular receptors regulating signaling, such as Fc receptors and integrins, are natural components to study. As these are complex systems to study, the lab is continuously developing new technology to improve the range and quality of the research, including smart and data-driven approaches to microscopy. The results from the research aim to improve our understanding as well as introduce new diagnostic and treatment options for infections and cancer. Recently, a significant focus has been on developing monoclonal antibodies against human pathogens.
Group Members
Berit Olofsson
Martin Sundwall
Oscar André
Karl Johansson
Arman Izadi
Vibha Kumra Ahnlide
Johannes Kumra Ahnlide
Louise Vulkan
Sanja Popovic
Hannah Heil