My research interests are molecular mechanisms and evolution of ribosomal protein synthesis and its regulation. The lab is using a combination of biochemical, microbiological, next-generation sequencing (ribosome profiling and 5PSeq) and structural (cryo-EM) approaches to tackle two complementary research directions:
- Phage-bacteria interactions: antiphage defence mechanisms, toxin-antitoxin systems
- Protein synthesis on the ribosome: antibiotics, antibiotic resistance, stress sensing and signalling, protein quality control