Wolfgang is an expert in protein production, enzymology and integrated structural biology approaches. As such he provides and develops life science infrastructure for protein production, protein characterization, biophysics and protein structure determination (www.lp3.lu.se & www.pps.gu.se/en). His research beýond the infrastructures features biochemical – structural biology approaches to study enzymes.
Wolfgang Knecht
Key Publications
A mild skeletal phenotype with overlapping features of Miller syndrome and functional characterisation of two new variants of human dihydroorotate dehydrogenase
Heliyon, 2024
Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome
Nucleosides, Nucleotides & Nucleic Acids, 2022
Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome
Nucleosides, Nucleotides & Nucleic Acids, 2022
Preparation of human dihydroorotate dehydrogenase for interaction studies with lipid bilayers
Nucleosides, Nucleotides & Nucleic Acids, 2020
The pathway to pyrimidines: The essential focus on dihydroorotate dehydrogenase, the mitochondrial enzyme coupled to the respiratory chain
Nucleosides, Nucleotides & Nucleic Acids, 2020