Sara Sandin

Head of Unit: Cryo-EM, Umeå University

Keywords
Key publications

Zhao X, Vogirala VK, Liu M, Zhou Y, Rhodes D, Sandin S, Yan J.
Exploring TRF2-Dependent DNA Distortion Through Single-DNA Manipulation Studies.
Commun Biol. 2024 Feb 3;7(1):148. doi: 10.1038/s42003-024-05838-x.

Hübner B, von Otter E, Ahsan B, Wee ML, Henriksson S, Ludwig A, Sandin S.
Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy.
Nucleic Acids Res. 2022 May 20;50(9):5047-5063. doi: 10.1093/nar/gkac309.

Chua EY, Vogirala VK, Inian O, Wong AS, Nordenskiöld L, Plitzko JM, Danev R, Sandin S. 3.9
A structure of the nucleosome core particle determined by phase-plate cryo-EM.
Nucleic Acids Res. 2016 Sep 30;44(17):8013-9. doi: 10.1093/nar/gkw708.

SciLifeLab / Contact / Sara Sandin

The Cryo-EM Swedish Infrastructure Unit offers access to state-of-the-art equipment and expertise in single particle analysis and cryo electron tomography. The Unit has two nodes: at SciLifeLab in Stockholm and at the Umeå Centre for Electron Microscopy (UCEM) at Umeå University. We provide service and user training for all aspects of cryo-EM projects, including project planning, sample preparation, screening, data collection and data analysis.

The UCEM laboratory is equipped with:

• Titan Krios G2 300kV cryo TEM, Falcon 4i Selectris
• Glacios 200kV cryo TEM, Falcon 4i
• Talos 120kV TEM, Ceta CMOS
• Aquilos 2 cryo FIB-SEM
• Thunder cryo widefield microscope
• Vitrobot plunge freezer
• EM GP2 plunge freezer

Group members

Erin Schexnaydre
Johan Unge
Agnieszka Ziolkowska
Tanvir Shaikh

Last updated: 2025-01-17

Content Responsible: David Gotthold(david.gotthold@scilifelab.se)