Clinical Genomics Örebro
Clinical Genomics Örebro was established in 2019 as a collaborative effort between the Department of Laboratory Medicine and the Clinical Research Laboratory (KFL) at Örebro University Hospital together with Örebro University.
Applications
We provide expertise, method development and end-to-end service to translational research and precision diagnostics for the development of tomorrow’s diagnostics. Our current disease focus areas are:
- Cancers (including solid tumors and hematological malignancies)
- Rare inherited disease
- Microbial diseases and surveillance
Services
Our national services within NGS and other molecular technologies include development of methods for clinical implementation or translational research with strong clinical utility. These include, but are not restricted to:
- Consultation (Project design, Target capture design, Data analysis)
- Sample management (Tissue processing, Resistance typing)
- QC of samples for various analyses (Sequencing data, Genomic DNA/RNA)
- Sequencing:
- DNA sequencing (WES, Panels, microbial genomes, metagenomics)
- Other molecular technologies (Digital droplet PCR)
- User access service (DNA/RNA concentration measurements, Automated electrophoresis for DNA/RNA, Sequencing)
- Bioinformatics (Bioinformatic analysis (data generated at CG or elsewhere))
- Clinical interpretation (Variants)
Equipment
Our node has access to specialized equipment that enable us to factilitate the translation of new high-throuput techniques into clinical use. These include, but are not restricted to:
- Various automatic robotic systems (Hamilton NGS Star, Myra Liquid Handling Station, Magnis NGS Prep system, Tecan Fluent 480)
- Various systems for QC, quantification and fragment analyses (TapeStation, Quantification using fluorescent assay (Qubit, Quantit))
- Instrumentation for Sanger sequencing (ABI 3500)
- Instrumentation for real time PCR and ddPCR (BioRad qPCR, QX200 Droplet Digital PCR System, ABI 7500)
- Sequencing platforms:
- Illumina (MiSeq, NextSeq 550 Dx, NextSeq 2000)
- Ion Torrent (Ion S5 Prime)
- Nanopore (MinION, GridION)
Accessing the Local Unit
To request a service, please visit iLab Organizer :: Clinical Genomics Örebro (ilabsolutions.com)
If you do not find the service or technology you require, contact us at info-clinical-genomics@scilifelab.se
