ADME of Therapeutics (ADMEoT) is the SciLifeLab DDD platform unit for absorption, distribution, metabolism, excretion (ADME), and preclinical profiling.
ADMEoT uses a state of the art laboratory and cutting edge research to help Swedish academic projects in the optimization of hit compound series and deliver lead compounds and candidate drugs of the highest possible quality. We add scientific value to all stages of the preclinical drug discovery and development process.
ADMEoT, as a part of UDOPP (a local platform at the Department of Pharmacy, Uppsala University), is also affiliated with two Innovative Medicines Initiative (IMI) projects: 1) European Gram-negative Anti-bacterial Engine (ENABLE) consortium – as the In Vitro ADME unit; 2) ConcePTION – as a team responsible for bioanalysis of human samples and population PK (popPK) modelling.
Determination and prediction of physico-chemical properties:
ADME (Absorption, Distribution, Metabolism, Excretion):
Liquid Chromatography-Mass spectrometry (LC-MS):
Design and evaluation of pharmacokinetic (PK) studies
Physiological-based pharmacokinetics (PBPK) simulations
Drug Optimization and Pharmaceutical Profiling (UDOPP),
Department of Pharmacy,
Box 580, Husargatan 3,
SE-751 23 Uppsala, Sweden
Visitor address / Deliveries
Uppsala University Drug Optimization and Pharmaceutical Profiling (UDOPP),
Department of Pharmacy, BMC, House B3, 3rd floor,
Please find a map and more instructions here.