Chemical Biology Consortium Sweden

CBCS provides state-of-the-art infrastructure and expertise to support the discovery, development, and application of high-quality bioactive small molecules for life science research. Our platform is designed to enable the exploration of complex biology across a wide range of applications.
For detailed information, please visit the CBCS external webpage.

Founded in 2010 and now part of SciLifeLab, CBCS operates through a network of national units, with core facilities at Karolinska Institutet and Umeå University, and local access nodes at Lund, Gothenburg, Linköping, and Uppsala Universities. Each site offers specialised expertise, including phenotypic profiling, ion channel screening, biosafety level 3 screening, and industry collaborations.

CBCS services include

• Access to large-scale small-molecule libraries (SciLifeLab Compound Collection, ~350,000 compounds)
• Robotic platforms for high-throughput screening (biochemical, cell-based, phenotypic)
• High-throughput imaging technologies
• Expertise in assay development, automation, and antimicrobial/plant-based screening
• Hit identification and optimisation
• Computational chemistry, cheminformatics, and molecular modelling
• Medicinal and synthetic chemistry support
• Target identification through chemical proteomics
• Mechanism of action (MoA) studies
• Access to the SPECS Drug Repurposing library through the Compound Center

Click HERE for more Information on our available services.

Project engagement

CBCS works through a collaborative research model. Large collaborative projects undergo a formal application process to ensure transparent prioritisation based on scientific excellence, novelty, feasibility, and relevance. An independent Project Review Committee, including academic and industry experts, reviews project proposals.

Smaller projects are handled on a first-come, first-served basis. Our nodes at Karolinska Institutet and Umeå University also offer open access to instrumentation. For more information, please contact any of our nodes or read more about our application process here.

Upcoming dates for Project Review Committee (PRC) meeting and the proposal submission deadline are published on our website www.cbcs.se

Nodes