Spatial Transcriptomics

Spatial Transcriptomics is a method that allows visualization and quantitative analysis of the transcriptome in individual tissue sections. By placing histological sections on glass slides with arrayed oligonucleotides containing positional barcodes, it is possible to generate high quality cDNA libraries with precise positional information for RNA-sequencing. This provides transcriptome data in a versatile format for bioinformatics analyses of gene expression within the tissue context, which will be valuable in both research and diagnostics. Spatial Transcriptomics technology is the first method to provide unbiased whole transcriptome analysis with spatial information from tissue sections.

NGI provides Spatial Transcriptomics as a service in collaboration with the Single Cell and Spatial Biology platform. NGI is also part of this new platform since 2021.