Swedish NMR Centre

The Swedish NMR Centre is an international, national and local research infrastructure that provides access to state-of-the-art NMR instrumentation and methodology, specifically within

• Structural biology
• Metabolomics
• Chemical biology and small molecule NMR
• DNP NMR

Swedish NMR Centre comprises two nodes, in Gothenburg and Umeå, with complementary competences. The Gothenburg node has much focus on structural biology and metabolomics studies on liquids, whereas Umeå can cater for solid-state NMR metabolomics studies. Both nodes have capability for fragment-based screening. Future development includes expansion to include solid state NMR also in Gothenburg as complement for the high-end solid state biomolecular NMR performed in Umeå. of For more information, please visit us at Gothenburg or Umeå.

Project applications

You are welcome to apply for a project through our portal.

Equipment

NMR spectrometers and main probe configuration

Gothenburg – Specialised in liquid state NMR

• 900 MHz magnet: Bruker Avance III HD console and 3 mm TCI cryoprobe – Superior sensitivity
• 800 MHz magnet: Bruker Avance III HD console, 3 mm TCI cryoprobe – Almost as good as 900MHz
• 800 MHz magnet: Bruker Avance III HD console, SampleJet sample changer, 5 mm TXO cryoprobe – Excellent sensitivity for ¹³C detection and used for dissolution DNP measurements
• 600 MHz magnet: Bruker NEO console, Cooled SampleJet, 5mm QCIP probe
• 700 MHz magnet: Avance III HD console, SampleJet sample changer, 5 mm QCI cryoprobe – ¹⁹F detection
• 600 MHz magnet: Avance III HD console, cooled SampleJet sample changer, alternately a 5 mm RT BBI probe for Bruker IVDr operation or a 5 mm diffusion/imaging probe – Metabolomics, metabolomics, metabolomics
• 400MHz magnet: DNP instrument with super high sensitivity

Umeå – State of the art equipment for solid state NMR

• 850 MHz magnet equipped with Avance III HD spectrometer, 5mm TXI cryoprobe, sample changer
• 600 MHz magnet equipped with Avance III, cooled SampleJet sample changer, Cryo-MAS probe
• 500 MHz Avance III

Sample preparation equipment

Gothenburg

• Bruker SamplePro L liquid handling robot
• Agilent Bravo liquid handling robot

Umeå

• Bruker SamplePro L liquid handling robot