[The Svedberg seminar] – Genome organisation and patterns of molecular evolution
December 1, 2025 @ 15:15 – 16:15 CET
Jennifer James
Assistant Professor DDLS Fellow
Bio
Dr. Jennifer James did her PhD in population genetics with Adam Eyre-Walker at the University of Sussex. After a postdoctoral position at the University of Cambridge she moved to the US, where she worked as a postdoctoral researcher with Joanna Masel at the University of Arizona, which introduced her to the world of proteomics. She next moved to Uppsala and worked as a postdoctoral research fellow with Martin Lascoux prior to becoming a DDLS fellow and starting her own new research group in Molecular Evolution. Her group conducts research on patterns of molecular evolution both at the genome and proteome level, with a focus on understanding mutational robustness.
Genome organisation and patterns of molecular evolution
In my group, we try to understand patterns of phenotypic evolution at the proteome level, and molecular evolution across the genome. Key to this question is understanding how the genome is structured and organised. For example, how pleiotropic are the effects of genes on average, and how complex are gene networks? To give one case, if pleiotropy is universal, such that all genes affect all traits, we expect all new mutations to have the same effect on fitness. However, the extent of pleiotropy in real biological systems remains debated. In this seminar I will discuss our
Host: Siv Andersson siv.andersson@icm.uu.se, UU
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