Researcher in Fluorescence Microscopy and Spectroscopy with Smart Probes

School of Engineering Sciences at KTH

Job description

Come join our team as a Researcher and become part of a dynamic and innovative research department located at Scilifelab. Our research group is dedicated to advancing scientific knowledge and exploring new frontiers in the field of fluorescence microscopy. As a member of our team, you will have the opportunity to work with cutting-edge technology and collaborate with a talented group of researchers, gaining invaluable experience and contributing to groundbreaking discoveries in the field.

The subject of the position centers around the development and validation of new techniques and tools in the field of fluorescence microscopy. This includes designing and implementing experiments to improve the resolution, accuracy, and sensitivity of fluorescence microscopy, as well as optimizing imaging protocols and developing new functional imaging modalities for specific biological applications. The Researcher will work in a dynamic, interdisciplinary team to drive innovation and develop cutting-edge technologies in the field of super-resolution microscopy, with the ultimate goal of advancing our understanding of biological systems and improving human health.

Specifically, the successful candidate will spearhead a research project focused on using smart fluorescent probes to advance fluorescent anisotropy techniques for measurement of rotational diffusivity in biological samples with super-resolution capabilities. Collaboration with other team members will be key to optimizing imaging protocols and tailoring techniques to address specific biological questions.

What we offer

• A position at a leading technical university that generates knowledge and skills for a sustainable future.
• Engaged and ambitious colleagues along with a creative, international and dynamic working environment
• Work in Stockholm , in close proximity to nature
• Help to relocate and be settled in Sweden and at KTH

Read more about what it is like to work at KTH

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree in Physics/Physical Chemistry
• Deep understanding of fluorescence imaging principles and techniques
• Expertise in super-resolution fluorescence microscopy, especially in STED/RESOLFT
• Experience in rotational-diffusivity measurement with photo-switching fluorophores
• Experience in characterization of fluorescent proteins and smart probes
• Experience in the development of optical systems for microscopy and spectroscopy
• Experience with time-resolved fluorescence, FLIM and fluorescence anisotropy
• Wet-lab experience in order to process samples
• Experience in mentoring PhD and master’s students
• Successful record of grant writing and funding acquisition
• Proven track record of producing high-quality research
• Fluent in written and oral English, necessary to collaborate in the international scientific working environment and to produce high quality publications

Preferred qualifications

• Experience in scientific computing and mathematical modeling for simulation of molecular photo-physics observables (e.g. kinetics and spectroscopical responses)
• Experience in programming for hardware control in LabVIEW/Python
• Experience in the development of optical system with components from major off-the shelf providers like Thorlabs/Newport
• Experience with multi-photon microscopy or other non-linear optical techniques
• Experience in image processing and analysis with ImageJ/Fiji/Python/MATLAB
• Experience with advanced rigid labelling and tagging strategies for orientational studies with fluorescent proteins and probes
• Interest in applying deep-learning and AI to imaging problems
• Experience with live-cell imaging techniques and protocols
• Knowledge of diversity and equal opportunity issues, with specific focus on gender equality 
• Collaborative abilities.
• Independence.

Great emphasis will be placed on personal skills.

Trade union representatives

You will find contact information to trade union representatives at KTH’s webbpage.

To apply for the position

Log into KTH’s recruitment system in order to apply for this position. You are the main responsible to ensure that your application is complete according to the ad. Your complete application must be received at KTH no later than the last day of application.

The application must include:

• CV including relevant professional experience and knowledge.
• Copy of diplomas and grades from your previous university studies. Translations into English or Swedish if the original documents have not been issued in any of these languages.
• Brief account of why you want to conduct research, your academic interests and how they relate to your previous studies and future goals. Max two pages long.

Your complete application must be received by KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time). 

About the employment

The employment is valid until further notice (permanent post) according to agreement.
The employment begins with a six-month probationary period.

Other information

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

For information about processing of personal data in the recruitment process please read here.

The position may include security-sensitive activities. To become authorized, you therefore need to pass a possible security check.

We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.

Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence

About KTH

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy. Read more here