DDLS Bioinformatics Support
The Bioinformatics Long-Term Support at SciLifeLab strives to enable excellent and Data-Driven Life Science, by ensuring that peer-reviewed research projects have access to advanced bioinformatics and data science competence, and by providing knowledge transfer and broad community training.
The Bioinformatics Long-Term Support at SciLifeLab strives to enable excellent and Data-Driven Life Science, by ensuring that peer-reviewed research projects have access to advanced bioinformatics and data science competence, and by providing knowledge transfer and broad community training. The bioinformatics support staff is also strongly promoting and applying Reproducible Research, Open Science and FAIR data handling.
Applications will be reviewed three times a year, with application deadlines typically in January, May and October.
Note! Cryo-EM/structural biology support
As of 2023, DDLS bioinformatics support also offers computational expertise for structural biology projects involving Cryo-EM and Cryo-ET data, potentially combined with other structural biology and structure prediction methods.
Please use the link above.
Curious about what we work on? Please see our project list.
About bioinformatics support at SciLifeLab
The Bioinformatics Long-term Support at SciLifeLab is operated by the SciLifeLab bioinformatics platform (NBIS) and offers extensive bioinformatics support to a limited set of scientifically outstanding projects. This support has been enabled primarily by a generous grant fromKnut and Alice Wallenberg Foundation (KAW) and through the Data-Driven Life Science program. The idea is simple: A senior bioinformatician will work on your project for 500 hours for free! Hands-on involvement by the applying research group is required to ensure efficient knowledge transfer.
The Long-Term Support team has internationally competitive expert knowledge in large-scale molecular data analyses and data science. The staff are experts in genomics, transcriptomics, proteomics, epigenetics, metagenomics, metabolomics, single-cell analyses, multi-omics integration and AI/Machine Learning applications, and our joint experience spans across many types of organisms and include projects from both medical, ecological and evolutionary research across all the four Research Areas of the DDLS program. More information about the all types of bioinformatics project support offered by DDLS and SciLifeLab including application and selection criteria for the Long-term Support is found at the NBIS Bioinformatics Support pages.
In addition, all Bioinformatics support staff are also heavily engaged in community training, for example through theSciLifeLab courses and the DDLS training program. The bioinformatics support staff also aim to take a leading role in implementing Reproducible Research, Open Science and FAIR data, working closely with the NBIS Data Management team and the SciLifeLab Data Platform.
Approved projects 2025
| Project title | Applicant | Organization |
|---|---|---|
| Single-cell analysis of the immune response in cardiac inflammation | Alexandru Schiopu | LU |
| Capsid assembly and genome packaging mechanism of an algal bloom-regulating virus | Anna Munke | LU |
| Regulatory principles of hypoxia transcriptional cell states | Bjørt Katrinardóttir Kragesteen | KI |
| CryoET reconstruction of membrane associated scaffold | Carsten Mim | KTH |
| Spatial multiomics to target the non-random metastatic behavior of cancer | Catharina Hagerling | LU |
| Gene regulatory networks in airway development and homeostasis | Christos Samakovlis | SU |
| Unravelling the molecular signatures of reproductive mood disorders | Donghao Lu | KI |
| Comparative genomics at the re-birth of a sustainable fibre crop | Edouard Pesquet | SU |
| The genomics of polymorphism across evolutionary scales. | Erik Svensson | LU |
| Therapeutic proteins for neurodegenerative diseases by computational design | Greta Hultqvist | UU |
| Single cell and Pixelgen analysis of Sjögren´s disease with lymphoma | Gunnel Nordmark | UU |
| Advanced genomics coupled with a data-driven framework to study mechanisms leading to immunity against malaria in the liver | Johan Ankarklev | SU |
| Adult Human Striatal Neurogenesis | Jonas Frisén | KI |
| Structural analysis of the polymodal ligand-gated ion channel LGC-39 | Julia Morud Lekholm | GU |
| Longitudinal proteomics analyses of genetics, aging, and dementia | Karolina Kauppi | UMU |
| Regulatory logic of endothelial cells | Kaska Koltowska | UU |
| The Multiple Sclerosis Exposome | Kim Kultima | UU |
| Somatic mutations and mutational processes in the human arterial wall | Maria Eriksson | KI |
| Uncovering proteomic alterations in PD using iPSC-derived brain cells | Melinda Rezeli | LU |
| Single-cell profiling of immune cells across the human lung | Nicole Marquardt | KI |
| Sequencing mtDNA mutations to understand aging and disease pathology | Nils-Göran Larsson | KI |
| Cryo-EM studies of the ubiquinone supercomplex from E. coli | Pål Stenmark | SU |
| Spatial host-microbiome interactions in the human and mouse gut | Stefania Giacomello | KTH |
| CNS waste disposal – molecular mechanism for controlling AQP4 localization | Susanna Horsefield | LU |
DDLS Data Science Nodes
In the end of May 2022, the SciLifeLab board appointed four national Data Science Nodes (DSNs) as part of the DDLS initiative. The four nodes, one for each DDLS research area, will coordinate and develop national services for databases and data support as well as bioinformatics support to the Swedish research community.
DDLS Data Science Nodes recruitment
All Data Science Nodes and Data Platform staff will be recruited to the participating organizations, enabling them to interact closely with local research and technology environments
The principles of the DDLS Bioinformatics support is described here.
Contact: bioinformatics_wabi@scilifelab.se