Integrated Structural Biology workshop
August 23 @ 08:00 – August 24 @ 16:30 CEST
Structural Biology comprises studies of proteins and nucleic acids, how they interact and how they appear in solution. The answer provides insight in to the function of the macromolecules and can explain diseases, basic functions or be used to understand mechanisms and in the longer perspective aim in drug design to name a few of the important areas where the techniques contributes.
Important techniques for structural biology include Cryo-EM, Nuclear Magnetic Resonance and Structural Proteomics and all of these are available through SciLifeLab. For a structural biology project, there is a pipeline starting with the gene and the end goal information is how and where the encoded protein functions or interacts with the surround.
It has become clear over the years that no technique alone can provide a full insight into a biological problem. Thus an integrated approach where different techniques are combined is often necessary. The aim for us working with structural biology at SciLifeLab is to be a partner along the whole way, from gene to final answer.
Program
Day 1
We will hear from Swedish infrastructures, covering the whole pipeline from gene to 3D protein structure and the subsequent functional analysis, in addition to computational aspects including AlphaFold.
Day 2
Day 2 will contain a general overview of structural biology and available techniques. There will also be a few presentations from participants that are given the chance to discuss and get feedback on their own project from participants but also from the infrastructure representatives. We will also have a time slot to discuss the availability of infrastructures in Sweden and if there are missing parts or suggestions for changes from the users.
cecilia.persson@nmr.gu.se
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