Exploring the Complexity of Life by Cryo-EM

Major technical advances has enabled cryo-EM to become a mainstream technique in visualization of macromolecules, which provides the most definitive way to describe their mechanisms of action. The first international cryo-EM symposium in Sweden will take place in Stockholm (May 8) and Umeå (May 9), and present the developments that are shaping this scientific breakthrough. Topics covered include central discoveries in cryo-EM, the most recent methodological developments and applications to central biological questions.

Please not that the venue has change to Gard-Aulan, Nobels väg 18, Solna (Folkhälsomyndigheten). This is due to the great interest in the symposium.

Everyone is welcome!

Program, May 8 (Stockholm)

08.45 Welcome
Gard-Aulan, Folkhälsomyndigheten, Nobels väg 18, Solna
09.00 Greetings
Göran Sandberg, executive director of the Wallenberg Foundation
09.10 Early time in cryo-EM microscopy
Jacques Dubochet, University of Lausanne, Switzerland
09.50 New frontiers in single-particle cryo-EM: imaging short-lived states and tracking a continuum of states
Joachim Frank, Columbia University, United States
10.30 Coffee
11.00 Atomic resolution cryo-EM
Sriram Subramaniam, National Institute of Health, United States
11.45 A molecular movie of the exitation-contraction coupling
Nieng Yan, Tsinghua University, China
12.30 Lunch and posters
Air & Fire auditorium, SciLifeLab
14.00 Mitochondrial membrane proteins and the resolution revolution in cryo-EM
Werner Kühlbrandt, MPI Biophysics, Germany
14.45 Single particle analysis of small molecules with the Volta phase plate
Radostin Danev, MPI Biochemistry, Germany
15.30 Coffee
16.00 Next steps for automation in cryo-EM
Bridget Carragher, NYSBC, United States
16.30 Cryo-EM methods that drive the revolution: example applications in Alzheimer’s disease
Sjors Scheres, MRC-LMB, United Kingdom
17.00 Future software development challenges in cryo-EM
Jose Miguel de la Rosa Trevin, Cryo-EM Facility, Sweden
17.30 Closing remarks
Gunnar von Heijne, Director of the Swedish National Cryo-EM Facility


Registration form, May 8 (Stockholm)

Please enter your details to attend the symposium in Stockholm. To register for Umeå, please see below.

Exploring the Complexity of Life by Cryo-EM
Please list requirements (if any)
The personal data you provide in this registration form is to enable SciLifeLab to register and contact you about your attendance at the event; Carry out administrative and planning activities for the event; Facilitate your requirements in relation to the event; Allow the compilation and analysis of statistics relevant to the event. The information you provide will be processed in accordance with the Swedish Personal Data Act (Personuppgiftslagen, SFS 1998:204) which is based on Directive 95/46/EC of the European Parliament and of the Council of 24 October 1995 on the protection of individuals with regard to the processing of personal data and on the free movement of such data. The following parties have access to your personal data: KTH: administration staff at SciLifeLab. Under the Personal Data Act (1998:204) anyone registered in KTH's register is entitled to receive information about what data has been registered. An application for a register extract has to be made in writing and signed personally. The application should be sent to: KTH, Personal data representative, Brinellvägen 8, SE-1 00 44 Stockholm.


Program, May 9 (Umeå)

09.00 Reducing the cost and increasing the speed of cryoEM
Richard Henderson, MRC Laboratory of Molecular Biology, Cambridge, UK
09.45 Structures of scarce native complexes by cryo-EM: Finally following eukaryotic ribosome biogenesis at molecular resolution
Roland Beckmann, Gene Center, University of Munich LMU, Germany
10.30 Coffee and posters
11.00 Single particle analysis of chromatin complexes
Sara Sandin, Nanyang Technological University, NTU, Singapore
11:45 Protein synthesis in organelles at cryo-EM resolution
Alexey Amunts, Stockholm University
12.30 Lunch and posters
14.00 Opening windows into the cell:  Revealing the molecular  architecture of the nuclear periphery
Elizabeth Villa, University of California, San Diego, USA
14.45 A Hitchhiker’s guide to cryo-tomography: travel tips on things to do
Elisabeth Fischer, National Institute of Health, Hamilton, MT, USA
15.30 Coffee and posters
16.00 Using new methods in cryo-EM to gain mechanistic insight into gene expression
Lori Passmore, MRC Laboratory of Molecular Biology, Cambridge, UK
16.45 Enabling and doing structural biology in situ – Recent advances in cryo-electron tomography
Jürgen Plitzko, Max Planck Institute of Biochemistry, Martinsried/Munich, Germany
17.30 Closing remarks

Registration, May 9 (Umeå)

Separate registration for the Umeå Symposium May 9 at: