Cell of origin influences glioma development and phenotype
Children with the malignant brain tumor form high-grade malignant glioma often have a very poor prognosis. The knowledge about how this cancer form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University/SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the tumor originates as well as the age of the patient. The cell of origin also affects tumor susceptibility to treatment.
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