Bernhard Schmierer

Platform Co-Director: Chemical Biology and Genome Engineering, Karolinska Institutet

Head of Unit: CRISPR Functional Genomics

Keywords
, , ,
Key Publications
Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity
Nature Communications, 2025
Read more
CRISPR-Cas9 Knockout Screens Identify DNA Damage Response Pathways and <i>BTK</i> as Essential for Cisplatin Response in Diffuse Large B-Cell Lymphoma
Cancers, 2024
Read more
Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell model.
EJNMMI radiopharmacy and chemistry, 2024
Read more
An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver.
Nature communications, 2023
Read more
Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action.
Frontiers in oncology, 2022
Read more
SciLifeLab / Contact / Bernhard Schmierer

My research is focused on development and implementation of novel applications of CRISPR systems in basic research. Examples include defining genetic factors affecting the delivery of CRISPR/Cas into cells, applying base-editing for scanning mutagenesis screens, and refining methods for pooled genetic screening with different CRISPR/Cas modalities.

Group Members

Soniya Dhanjal
Olga Khorosjutina
Anneke Navis
Miriam Selle

Last updated: 2025-01-29

Content Responsible: Hampus Pehrsson Ternström(hampus.persson@scilifelab.uu.se)

Help Us Improve!
We want to better match our services with your needs—take our short survey and help shape SciLifeLab’s digital future. You can also join our user panel for occasional feedback opportunities and early access to new tools.
Take the survey
Help Us Improve!
We want to better match our services with your needs—take our short survey and help shape SciLifeLab’s digital future. You can also join our user panel for occasional feedback opportunities and early access to new tools.
Take the survey