Katarina Tiklova

Head of Unit: In Situ Sequencing, Stockholm University

Key publications

(2024) A community effort to track commercial single-cell and spatial ‘omic technologies and business trends.
De Jonghe J, Opzoomer JW, Vilas-Zornoza A, Crane P, Nilges BS, Vicari M, Lee H, Lara-Astiaso D, Gross T, Morf J, Schneider K, Cudini J, Ramos-Mucci L, Mooijman D, Tiklová K, Salas SM, Langseth CM, Kashikar ND, Roberts CES; scTrends Consortium; Lundeberg J, Nilsson M, Shalek AK, Cribbs AP, Taylor-King JP.
Nat Biotechnol. 2024 Jul;42(7):1017-1023. 

(2024) Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology.
Kukanja P, Langseth CM, Rubio Rodríguez-Kirby LA, Agirre E, Zheng C, Raman A, Yokota C, Avenel C, Tiklová K, Guerreiro-Cacais AO, Olsson T, Hilscher MM, Nilsson M, Castelo-Branco G.
Cell. 2024 Apr 11;187(8):1990-2009.e19. 

(2023) Padlock Probe-Based Targeted In Situ Sequencing: Overview of Methods and Applications.
Magoulopoulou A, Salas SM, Tiklová K, Samuelsson ER, Hilscher MM, Nilsson M.
Annu Rev Genomics Hum Genet. 2023 Aug 25;24:133-150. 

My work focuses on spatial transcriptomics through imaging-based in situ sequencing, with an emphasis on the Xenium platform. I apply this technology across diverse fields, including cancer research, neurobiology, developmental biology, and tissue atlasing. Driven by a strong interest and passion for integrated omics, my goal is to analyze multiple modalities within the same tissue sections, unlocking their full potential to enable transformative advancements in diagnostic applications.

Last updated: 2025-01-16

Content Responsible: Hampus Persson(hampus.persson@scilifelab.uu.se)