Key publications

Arimide DA, Szojka ZI, Zealiyas K, Gebreegziabxier A, Adugna F, Sasinovich S, Bjorkman P and Medstrand P. Pre-Treatment Integrase Inhibitor Resistance and Natural Polymorphisms among HIV-1 Subtype C Infected Patients in Ethiopia. Viruses (Basel). 2022;14(4).

Arimide DA, Esquivel-Gomez LR, Kebede Y, Sasinovich S, Balcha T, Bjorkman P, Kuehnert D and Medstrand P. Molecular Epidemiology and Transmission Dynamics of the HIV-1 Epidemic in Ethiopia: Epidemic Decline Coincided With Behavioral Interventions Before ART Scale-Up. Front Microbiol. 2022;13.

Alsved M, Nygren D, Thuresson S, Medstrand P, Fraenkel CJ and Londahl J. SARS-CoV-2 in Exhaled Aerosol Particles from COVID-19 Cases and Its Association to Household Transmission. Clin Infect Dis. 2022;75(1):E50-E6

Esbjornsson J, Mansson F, Kvist A, da Silva ZJ, Andersson S, Fenyo EM, Lsberg PE, Baigue AJ, Lindman J, Palm AA, Jones SLR, Jansson M, Medstrand P, Norrgren H. Long-term follow-up of HIV-2-related AIDS and mortality in Guinea-Bissau: a prospective open cohort study. Lancet HIV. 2019;6(1):E25-E31.

Alaridah N, Hallback ET, Tangrot J, Winqvistz N, Sturegard E, Floren-Johanssons K, Jonsson B, Tenland E, Welinder-Olssons C, Medstrand P, Kaijser B and Godaly G. Transmission dynamics study of tuberculosis isolates with whole genome sequencing in southern Sweden. Sci Rep. 2019;9.

Esbjornsson J, Mansson F, Kvist A, Isberg PE, Nowroozalizadeh S, Biague AJ, da Silva ZJ, Jansson M, Fenyo EM, Norrgren H, and Medstrand P. Inhibition of HIV-1 disease progression by contemporaneous HIV-2 infection. The New England journal of medicine 367: 224-232, 2012.

My team’s main goal is to create and improve diagnostic tools for detecting and quantifying viral infections and drug resistant virus, using next-generation sequencing approaches in the area of “pandemic preparedness.” Our current work entails a large number of collaborators, is establishing biobanks, and in the use of clinical and environmental specimens in our studies. Because of the SARS-CoV-2 pandemic, current research has concentrated on developing qPCR assays, targeted Spike mutation analysis, and whole genome Illumina sequencing of SARS-CoV-2. Ongoing research entails whole-genome sequencing of several viruses with pandemic and epidemic potential, including respiratory and blood-borne viruses.

Our group’s main research interests are to understand (1) the implications of genetic diversity and molecular properties of RNA viruses and the role this plays in immunopathogenesis, disease progression, and clearance, (2) the development of drug resistance, with a special focus on HIV drug resistance, and (3) the viral epidemiology of HIV, hepatitis C virus, and other RNA viruses. A significant portion of our research efforts are dedicated to public health, with an emphasis on HIV prevention, control, and surveillance. We collaborate in multidisciplinary teams with colleagues primarily in two Sub-Saharan African nations, Ethiopia and Guinea-Bissau.

Group Members

Sviataslau Sasinovich
Dawit Assefa Arimide
Sara Karlson
Malik Sallam
Ander Widell
Ilili Jemal Abdulahi

Last updated: 2023-04-06

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